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Journal of Medicinal Chemistry|July 18, 2025
Probing the Dominant Motifs within the Hydrophobic Channel Yields Oxadiazole-Containing Diarylpyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase InhibitorsTao Zhang, Yue Yang, Xin Li, et al.Chemical Communications (Cambridge, England)|July 17, 2020
Spinel-structure catalyst catalyzing CO<sub>2</sub> hydrogenation to full spectrum alkenes with an ultra-high yieldLisheng Guo, Jie Li, Yu Cui, et al.Bioorganic Chemistry|August 24, 2021
Discovery of potent and selective Cdc25 phosphatase inhibitors via rapid assembly and in situ screening of Quinonoid-focused librariesYucen Tao, Xia Hao, Lanlan Jing, et al.European Journal of Medicinal Chemistry|December 6, 2020
Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp<sup>3</sup> values and favorable drug-like propertiesXiangyi Jiang, Boshi Huang, Fisayo A Olotu, et al.Molecules (Basel, Switzerland)|September 23, 2022
Design, Synthesis, and Evaluation of a Set of Carboxylic Acid and Phosphate Prodrugs Derived from HBV Capsid Protein Allosteric Modulator NVR 3-778Xiangkai Ji, Xiangyi Jiang, Chisa Kobayashi, et al.Journal of Medicinal Chemistry|January 27, 2022
Discovery of Novel Bicyclic Imidazolopyridine-Containing Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Improved Efficacy and Favorable DruggabilityTong Zhao, Jian Zhang, Yucen Tao, et al.European Journal of Medicinal Chemistry|June 9, 2019
Design, synthesis and biological evaluation of "Multi-Site"-binding influenza virus neuraminidase inhibitorsRuifang Jia, Jian Zhang, Wei Ai, et al.Viruses|November 11, 2022
Structure-Based Discovery and Characterization of a Preclinical Drug Candidate for the Treatment of HIV-1 InfectionDongwei Kang, Jinxuan Yang, Lingjin Kong, et al.Bioorganic Chemistry|March 18, 2023
Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategiesLanlan Jing, Wenxiu Wei, Bairu Meng, et al.European Journal of Medicinal Chemistry|October 6, 2024
Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant virusesXiangyi Jiang, Waleed A Zalloum, Zhen Gao, et al.Pageof 56