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Journal of Medicinal Chemistry|July 3, 2018
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant VariantJian Zhang, Vasanthanathan Poongavanam, Dongwei Kang, et al.
Nature Communications|August 11, 2025
Discovery of multi-target anti-gout agents from Eurycoma longifolia Jack through phenotypic screening and structural optimizationZhijiao Zhang, Xiaoyu Shi, Ting Wu, et al.
Nature Communications|March 16, 2026
INSIG1/2 succination mediated by the moonlighting function of ADSL promotes lipogenesis and liver tumorigenesisYuran Duan, Shuo Wang, Jianyu Liu, et al.
Science Translational Medicine|November 15, 2023
Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse modelsShuaiya Ma, Ye Tian, Jiali Peng, et al.
Nature Chemical Biology|January 29, 2025
ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylationLei Wang, Runze Shi, Shuo Wang, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 31, 2025
Transferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARα hydroxylation in an iron-dependent mannerXu Qian, Qimin Zhou, Yuan Ouyang, et al.
Bioorganic & Medicinal Chemistry|June 4, 2024
A consensus reverse docking approach for identification of a competitive inhibitor of acetyltransferase enhanced intracellular survival protein from Mycobacterium tuberculosisPaulo Fernando da Silva Santos-Júnior, Vitoria de Melo Batista, Igor José Dos Santos Nascimento, et al.
European Journal of Medicinal Chemistry|December 9, 2024
Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like proteaseJéssica Alves Nunes, Paulo Fernando da Silva Santos-Júnior, Midiane Correa Gomes, et al.
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