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Cell Chemical Biology
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November 7, 2025
Development of D2HG biosensors inspired by the molecular mechanism of D2HG regulation of DhdR
Bin Wang, Shouqing Luo, Pengkai Sun
Cell Discovery
|
December 22, 2020
Structure and allosteric regulation of human NAD-dependent isocitrate dehydrogenase
Pengkai Sun, Yan Liu, Tengfei Ma, et al.
Scientific Reports
|
April 12, 2020
Molecular mechanism of the dual regulatory roles of ATP on the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase
Pengkai Sun, Tuya Bai, Tengfei Ma, et al.
Cell Metabolism
|
January 5, 2024
ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
Chao Chen, Zhenxing Zhang, Caiyun Liu, et al.
The Journal of Biological Chemistry
|
November 14, 2022
Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction
Xingchen Chen, Pengkai Sun, Yan Liu, et al.
Science Advances
|
March 7, 2025
Isocyanic acid-mediated NLRP3 carbamoylation reduces NLRP3-NEK7 interaction and limits inflammasome activation
Zhenxing Zhang, Chao Chen, Caiyun Liu, et al.
Nature Communications
|
November 5, 2022
A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages
Pengkai Sun, Zhenxing Zhang, Bin Wang, et al.
The Journal of Biological Chemistry
|
September 14, 2019
Molecular basis for the function of the αβ heterodimer of human NAD-dependent isocitrate dehydrogenase
Pengkai Sun, Tengfei Ma, Tianlong Zhang, et al.
Developmental Cell
|
August 8, 2024
Itaconate uptake via SLC13A3 improves hepatic antibacterial innate immunity
Chao Chen, Caiyun Liu, Pengkai Sun, et al.
Molecular Cell
|
June 6, 2022
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
Zhenxing Zhang, Chao Chen, Fan Yang, et al.
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Search research articles
Search
Showing results (1-10 of 18) with videos related to
Sort By:
Page
of 2
Cell Chemical Biology
|
November 7, 2025
Development of D2HG biosensors inspired by the molecular mechanism of D2HG regulation of DhdR
Bin Wang, Shouqing Luo, Pengkai Sun
Cell Discovery
|
December 22, 2020
Structure and allosteric regulation of human NAD-dependent isocitrate dehydrogenase
Pengkai Sun, Yan Liu, Tengfei Ma, et al.
Scientific Reports
|
April 12, 2020
Molecular mechanism of the dual regulatory roles of ATP on the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase
Pengkai Sun, Tuya Bai, Tengfei Ma, et al.
Cell Metabolism
|
January 5, 2024
ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
Chao Chen, Zhenxing Zhang, Caiyun Liu, et al.
The Journal of Biological Chemistry
|
November 14, 2022
Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction
Xingchen Chen, Pengkai Sun, Yan Liu, et al.
Science Advances
|
March 7, 2025
Isocyanic acid-mediated NLRP3 carbamoylation reduces NLRP3-NEK7 interaction and limits inflammasome activation
Zhenxing Zhang, Chao Chen, Caiyun Liu, et al.
Nature Communications
|
November 5, 2022
A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages
Pengkai Sun, Zhenxing Zhang, Bin Wang, et al.
The Journal of Biological Chemistry
|
September 14, 2019
Molecular basis for the function of the αβ heterodimer of human NAD-dependent isocitrate dehydrogenase
Pengkai Sun, Tengfei Ma, Tianlong Zhang, et al.
Developmental Cell
|
August 8, 2024
Itaconate uptake via SLC13A3 improves hepatic antibacterial innate immunity
Chao Chen, Caiyun Liu, Pengkai Sun, et al.
Molecular Cell
|
June 6, 2022
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
Zhenxing Zhang, Chao Chen, Fan Yang, et al.
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of 2