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Nature Communications
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October 17, 2015
Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
Qi Fei, Ke Shang, Jianhua Zhang, et al.
Cancer Research
|
August 28, 2013
NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma
Zheng Huang, Haiping Wu, Shannon Chuai, et al.
Plos One
|
January 11, 2017
Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
Ling Li, Hailong Zhang, Man Zhang, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 14, 2012
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation
Wei Qi, HoMan Chan, Lin Teng, et al.
Journal of Medicinal Chemistry
|
December 16, 2017
Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3)
H Ümit Kaniskan, Mohammad S Eram, Kehao Zhao, et al.
Journal of Medicinal Chemistry
|
January 17, 2017
Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy
Ying Huang, Jeff Zhang, Zhengtian Yu, et al.
Journal of Medicinal Chemistry
|
October 3, 2003
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)
Stacy W Remiszewski, Lidia C Sambucetti, Kenneth W Bair, et al.
Angewandte Chemie (International Ed. in English)
|
March 3, 2015
A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)
H Ümit Kaniskan, Magdalena M Szewczyk, Zhengtian Yu, et al.
Nature Chemical Biology
|
January 31, 2017
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED
Wei Qi, Kehao Zhao, Justin Gu, et al.
Journal of Medicinal Chemistry
|
June 10, 2011
Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors
Michael D Shultz, Xueying Cao, Christine H Chen, et al.
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Search research articles
Search
Showing results (91-100 of 102) with videos related to
Sort By:
Page
of 11
Nature Communications
|
October 17, 2015
Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
Qi Fei, Ke Shang, Jianhua Zhang, et al.
Cancer Research
|
August 28, 2013
NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma
Zheng Huang, Haiping Wu, Shannon Chuai, et al.
Plos One
|
January 11, 2017
Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
Ling Li, Hailong Zhang, Man Zhang, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 14, 2012
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation
Wei Qi, HoMan Chan, Lin Teng, et al.
Journal of Medicinal Chemistry
|
December 16, 2017
Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3)
H Ümit Kaniskan, Mohammad S Eram, Kehao Zhao, et al.
Journal of Medicinal Chemistry
|
January 17, 2017
Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy
Ying Huang, Jeff Zhang, Zhengtian Yu, et al.
Journal of Medicinal Chemistry
|
October 3, 2003
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)
Stacy W Remiszewski, Lidia C Sambucetti, Kenneth W Bair, et al.
Angewandte Chemie (International Ed. in English)
|
March 3, 2015
A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)
H Ümit Kaniskan, Magdalena M Szewczyk, Zhengtian Yu, et al.
Nature Chemical Biology
|
January 31, 2017
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED
Wei Qi, Kehao Zhao, Justin Gu, et al.
Journal of Medicinal Chemistry
|
June 10, 2011
Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors
Michael D Shultz, Xueying Cao, Christine H Chen, et al.
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of 11