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Brain Research|December 1, 2009
Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's diseaseNathan R Rustay, Elizabeth A Cronin, Peter Curzon, et al.
Biochemical Pharmacology|September 15, 2007
A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal modelsJianguo Ji, William H Bunnelle, David J Anderson, et al.
Brain Research. Molecular Brain Research|October 8, 2004
In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotideMonique R Adams, Arthur L Nikkel, Diana L Donnelly-Roberts, et al.
British Journal of Pharmacology|October 23, 2009
Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptorsClark A Briggs, Jens Halvard Grønlien, Peter Curzon, et al.
Journal of Medicinal Chemistry|December 22, 2006
Synthesis and structure-activity relationships of 3,8-diazabicyclo[4.2.0]octane ligands, potent nicotinic acetylcholine receptor agonistsJennifer M Frost, William H Bunnelle, Karin R Tietje, et al.
Journal of Medicinal Chemistry|June 26, 2007
Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptorsWilliam H Bunnelle, Jerome F Daanen, Keith B Ryther, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 28, 2007
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathwaysRobert S Bitner, William H Bunnelle, David J Anderson, et al.
Epilepsia|September 9, 2005
Preclinical profiling and safety studies of ABT-769: a compound with potential for broad-spectrum antiepileptic activityWilliam J Giardina, Michael J Dart, Richard R Harris, et al.
CNS Neuroscience & Therapeutics|May 17, 2008
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing propertiesKarin R Tietje, David J Anderson, R Scott Bitner, et al.
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