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Gastroenterology|December 13, 2025
Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults With α-1 Antitrypsin Deficiency-Associated Liver DiseaseRohit Loomba, Virginia C Clark, Mattias Mandorfer, et al.
American Journal of Respiratory and Critical Care Medicine|September 8, 2025
Randomized Sham-controlled Trial of Targeted Lung Denervation in Patients with Chronic Obstructive Pulmonary Disease (AIRFLOW-3)Pallav L Shah, Dirk-Jan Slebos, Richard Sue, et al.
Orphanet Journal of Rare Diseases|April 9, 2026
Z variant heterozygosity in alpha-1 antitrypsin deficiency: disease risk and treatment implicationsCraig P Hersh, Jeffrey H Teckman, Pavel Strnad, et al.
American Journal of Respiratory and Critical Care Medicine|November 16, 2017
Lymphangioleiomyomatosis Diagnosis and Management: High-Resolution Chest Computed Tomography, Transbronchial Lung Biopsy, and Pleural Disease Management. An Official American Thoracic Society/Japanese Respiratory Society Clinical Practice GuidelineNishant Gupta, Geraldine A Finlay, Robert M Kotloff, et al.
The Lancet. Respiratory Medicine|October 26, 2013
Serum VEGF-D a concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trialLisa Young, Hye-Seung Lee, Yoshikazu Inoue, et al.
The European Respiratory Journal|March 9, 2019
Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosisNishant Gupta, Hye-Seung Lee, Lisa R Young, et al.
Gastroenterology|July 4, 2024
Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA)Virginia C Clark, Charlie Strange, Pavel Strnad, et al.
Thorax|December 11, 2020
Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiencyJen-Hwa Chu, Wenlan Zang, Milica Vukmirovic, et al.
JAMA|May 16, 2016
Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical TrialFrank C Sciurba, Gerard J Criner, Charlie Strange, et al.
The New England Journal of Medicine|June 23, 2006
Cyclophosphamide versus placebo in scleroderma lung diseaseDonald P Tashkin, Robert Elashoff, Philip J Clements, et al.
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