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Journal of Medicinal Chemistry|July 15, 2024
Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical AssaysThomas Gerstberger, Helmut Berger, Frank H Büttner, et al.Journal of Medicinal Chemistry|October 25, 2016
Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 InteractionAndreas Gollner, Dorothea Rudolph, Heribert Arnhof, et al.Journal of the American Chemical Society|October 30, 2025
Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-Loaded KRAS(On) AllelesVesna Vetma, Ilaria Puoti, Natalia K Karolak, et al.Journal of Medicinal Chemistry|February 12, 2019
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding FunctionsJohannes Popow, Heribert Arnhof, Gerd Bader, et al.Molecular Cancer Therapeutics|February 7, 2020
Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor SurveillanceMarco H Hofmann, Rajeswaran Mani, Harald Engelhardt, et al.Plos One|August 3, 2017
Progress towards a public chemogenomic set for protein kinases and a call for contributionsDavid H Drewry, Carrow I Wells, David M Andrews, et al.Journal of Medicinal Chemistry|March 15, 2021
One Atom Makes All the Difference: Getting a Foot in the Door between SOS1 and KRASJuergen Ramharter, Dirk Kessler, Peter Ettmayer, et al.Blood|January 29, 2021
Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosisMarcelo A S Toledo, Malrun Gatz, Stephanie Sontag, et al.International Journal of Molecular Sciences|January 12, 2021
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability IdentificationCarrow I Wells, Hassan Al-Ali, David M Andrews, et al.Cancer Discovery|August 21, 2020
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK InhibitionMarco H Hofmann, Michael Gmachl, Juergen Ramharter, et al.Pageof 3