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Biochemistry|July 8, 2009
Steady-state and stopped-flow kinetic studies of three Escherichia coli NfsB mutants with enhanced activity for the prodrug CB1954David Jarrom, Mansooreh Jaberipour, Christopher P Guise, et al.Journal of Medicinal Chemistry|July 11, 2006
Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activationYongying Jiang, Jiye Han, Chengzhi Yu, et al.Journal of Molecular Biology|March 14, 2007
Kinetic and structural characterisation of Escherichia coli nitroreductase mutants showing improved efficacy for the prodrug substrate CB1954Paul R Race, Andrew L Lovering, Scott A White, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|September 3, 2010
Minimal RB-responsive E1A promoter modification to attain potency, selectivity, and transgene-arming capacity in oncolytic adenovirusesJuan J Rojas, Sonia Guedan, Peter F Searle, et al.Biochemical Pharmacology|August 12, 2009
Testing double mutants of the enzyme nitroreductase for enhanced cell sensitisation to prodrugs: effects of combining beneficial single mutationsMansooreh Jaberipour, Simon O Vass, Christopher P Guise, et al.FEBS Letters|June 1, 2022
The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP<sup>+</sup> provide glimpses of its catalytic mechanismScott A White, Andrew J Christofferson, Alastair I Grainger, et al.The Journal of Biological Chemistry|February 3, 2005
Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzymePaul R Race, Andrew L Lovering, Richard M Green, et al.Cancer Research|September 23, 2003
Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954Jane I Grove, Andrew L Lovering, Christopher Guise, et al.Journal of Medicinal Chemistry|October 31, 2003
Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapyLongqin Hu, Chengzhi Yu, Yongying Jiang, et al.The Biochemical Journal|June 18, 2021
The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMNMartin A Day, David Jarrom, Andrew J Christofferson, et al.Pageof 3