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Familial Cancer
|
November 10, 2025
The germline POLD1 c.1420 C > A (p.Leu474Ile) variant segregates with endometrial cancer, colorectal cancer and colonic polyps demonstrating hypermutation and defective POLD1 mutational signatures
Daniel D Buchanan, Peter Georgeson, Romy Walker, et al.
Familial Cancer
|
June 15, 2023
A mosaic pathogenic variant in MSH6 causes MSH6-deficient colorectal and endometrial cancer in a patient classified as suspected Lynch syndrome: a case report
Romy Walker, Mark Clendenning, Jihoon E Joo, et al.
Gastroenterology
|
March 18, 2023
Oncomicrobial Community Profiling Identifies Clinicomolecular and Prognostic Subtypes of Colorectal Cancer
Dmitri Mouradov, Paul Greenfield, Shan Li, et al.
Familial Cancer
|
July 9, 2026
Lynch syndrome caused by a pathogenic SINE-VNTR-Alu (SVA) insertion in MSH2 gene identified by long-read DNA sequencing
Jihoon E Joo, Khalid Mahmood, Mark Clendenning, et al.
Prostate Cancer and Prostatic Diseases
|
June 10, 2021
MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer
Patrick McCoy, Stefano Mangiola, Geoff Macintyre, et al.
The Journal of Molecular Diagnostics : JMD
|
December 31, 2020
Germline and Tumor Sequencing as a Diagnostic Tool To Resolve Suspected Lynch Syndrome
Bernard J Pope, Mark Clendenning, Christophe Rosty, et al.
Genome Research
|
November 12, 2021
Long-read assembly and comparative evidence-based reanalysis of <i>Cryptosporidium</i> genome sequences reveal expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions
Rodrigo P Baptista, Yiran Li, Adam Sateriale, et al.
Familial Cancer
|
January 31, 2026
Germline MLH1 c.-42 C > T is a likely pathogenic variant predisposing to a reduced-penetrance/modified Lynch syndrome phenotype featuring MLH1-methylated cancers
Daniel D Buchanan, Rocio Alvarez, Khalid Mahmood, et al.
Cancers
|
June 2, 2021
DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer
Jihoon E Joo, Mark Clendenning, Ee Ming Wong, et al.
Familial Cancer
|
December 8, 2023
Inherited BRCA1 and RNF43 pathogenic variants in a familial colorectal cancer type X family
James M Chan, Mark Clendenning, Sharelle Joseland, et al.
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Search research articles
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Showing results (11-20 of 47) with videos related to
Sort By:
Page
of 5
Familial Cancer
|
November 10, 2025
The germline POLD1 c.1420 C > A (p.Leu474Ile) variant segregates with endometrial cancer, colorectal cancer and colonic polyps demonstrating hypermutation and defective POLD1 mutational signatures
Daniel D Buchanan, Peter Georgeson, Romy Walker, et al.
Familial Cancer
|
June 15, 2023
A mosaic pathogenic variant in MSH6 causes MSH6-deficient colorectal and endometrial cancer in a patient classified as suspected Lynch syndrome: a case report
Romy Walker, Mark Clendenning, Jihoon E Joo, et al.
Gastroenterology
|
March 18, 2023
Oncomicrobial Community Profiling Identifies Clinicomolecular and Prognostic Subtypes of Colorectal Cancer
Dmitri Mouradov, Paul Greenfield, Shan Li, et al.
Familial Cancer
|
July 9, 2026
Lynch syndrome caused by a pathogenic SINE-VNTR-Alu (SVA) insertion in MSH2 gene identified by long-read DNA sequencing
Jihoon E Joo, Khalid Mahmood, Mark Clendenning, et al.
Prostate Cancer and Prostatic Diseases
|
June 10, 2021
MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer
Patrick McCoy, Stefano Mangiola, Geoff Macintyre, et al.
The Journal of Molecular Diagnostics : JMD
|
December 31, 2020
Germline and Tumor Sequencing as a Diagnostic Tool To Resolve Suspected Lynch Syndrome
Bernard J Pope, Mark Clendenning, Christophe Rosty, et al.
Genome Research
|
November 12, 2021
Long-read assembly and comparative evidence-based reanalysis of <i>Cryptosporidium</i> genome sequences reveal expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions
Rodrigo P Baptista, Yiran Li, Adam Sateriale, et al.
Familial Cancer
|
January 31, 2026
Germline MLH1 c.-42 C > T is a likely pathogenic variant predisposing to a reduced-penetrance/modified Lynch syndrome phenotype featuring MLH1-methylated cancers
Daniel D Buchanan, Rocio Alvarez, Khalid Mahmood, et al.
Cancers
|
June 2, 2021
DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer
Jihoon E Joo, Mark Clendenning, Ee Ming Wong, et al.
Familial Cancer
|
December 8, 2023
Inherited BRCA1 and RNF43 pathogenic variants in a familial colorectal cancer type X family
James M Chan, Mark Clendenning, Sharelle Joseland, et al.
Page
of 5