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Nature Communications|November 18, 2024
A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCRLior Peri, Donna Matzov, Dominic R Huxley, et al.The Journal of Biological Chemistry|September 24, 2025
SAG1.3-derived Frizzled-targeting small-molecule compoundsLukas Grätz, Ainoleena Turku, Pawel Kozielewicz, et al.Cell|May 29, 2024
Structure-based discovery of CFTR potentiators and inhibitorsFangyu Liu, Anat Levit Kaplan, Jesper Levring, et al.Nature Communications|April 14, 2023
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamicsXinyu Xu, Jeremy Shonberg, Jonas Kaindl, et al.Biorxiv : the Preprint Server for Biology|September 25, 2023
Structure-based discovery of CFTR potentiators and inhibitorsFangyu Liu, Anat Levit Kaplan, Jesper Levring, et al.Biorxiv : the Preprint Server for Biology|March 30, 2023
Time-resolved cryo-EM of G protein activation by a GPCRMakaía M Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, et al.Nature|March 14, 2024
Time-resolved cryo-EM of G-protein activation by a GPCRMakaía M Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, et al.Journal of Medicinal Chemistry|October 15, 2019
Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in VivoMatthias Scheiner, Dominik Dolles, Sandra Gunesch, et al.Antiviral Research|November 8, 2015
The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65Corina Hutterer, Ina Niemann, Jens Milbradt, et al.Nature Chemical Biology|June 3, 2020
An allosteric modulator binds to a conformational hub in the β2 adrenergic receptorXiangyu Liu, Jonas Kaindl, Magdalena Korczynska, et al.Pageof 25