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Ebiomedicine|April 13, 2025
A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosisJeremy S Lum, Mikayla L Brown, Natalie E Farrawell, et al.
Plos One|March 22, 2013
Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosisKatja M Kanninen, Alexandra Grubman, Jodi Meyerowitz, et al.
Sleep|November 11, 2020
A potential role for zinc in restless legs syndromePan Chen, Julia Bornhorst, Stephanie Patton, et al.
The Biochemical Journal|August 8, 2007
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligandsAphrodite Caragounis, Tai Du, Gulay Filiz, et al.
Scientific Reports|March 12, 2024
Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALSJames B W Hilton, Kai Kysenius, Jeffrey R Liddell, et al.
Disease Models & Mechanisms|June 27, 2013
Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse modelTheresa N T Dang, Carol Dobson-Stone, Elias N Glaros, et al.
Scientific Reports|September 30, 2021
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 backgroundJeremy S Lum, Mikayla L Brown, Natalie E Farrawell, et al.
Proteomics|April 4, 2008
Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarraysTai Du, Sharon L La Fontaine, Michael Abdo, et al.
Journal of Neurochemistry|July 30, 2011
The Alzheimer's therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activityPeter J Crouch, Maria S Savva, Lin W Hung, et al.
Molecular Neurodegeneration|August 9, 2011
C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stressJodi Meyerowitz, Sarah J Parker, Laura J Vella, et al.
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