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Journal of Medicinal Chemistry|January 12, 2026
Novel Scaffold Unlocks Potent Cross-Peptidase and Cross-Species Inhibitors as Promising Antimalarial AgentsMahta Mansouri, Amanda De Paoli, Carlo Giannangelo, et al.Scientific Reports|January 21, 2018
The action of a negative allosteric modulator at the dopamine D<sub>2</sub> receptor is dependent upon sodium ionsChristopher J Draper-Joyce, Ravi Kumar Verma, Mayako Michino, et al.Biochemistry|November 1, 2014
Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVOSan Sui Lim, Wei Yang, Bankala Krishnarjuna, et al.Journal of Medicinal Chemistry|June 13, 2020
Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL<sub>X</sub>)Matthew R Bentley, Olga V Ilyichova, Geqing Wang, et al.Journal of Medicinal Chemistry|January 7, 2015
Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffoldShane M Devine, Mark D Mulcair, Cael O Debono, et al.Biorxiv : the Preprint Server for Biology|November 24, 2025
Structure-guided allosteric modulation of the delta opioid receptorJesse I Mobbs, M Deborah Nguyen, Owindeep Deo, et al.Proceedings of the National Academy of Sciences of the United States of America|July 7, 2025
Structure-based discovery of positive allosteric modulators of the A<sub>1</sub> adenosine receptorAnh T N Nguyen, Nicolas Panel, Duc Duy Vo, et al.Elife|September 13, 2022
Genetic and chemical validation of <i>Plasmodium falciparum</i> aminopeptidase <i>Pf</i>A-M17 as a drug target in the hemoglobin digestion pathwayRebecca C S Edgar, Ghizal Siddiqui, Katheryn Hjerrild, et al.Mbio|May 8, 2024
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activityRebecca C S Edgar, Tess R Malcolm, Ghizal Siddiqui, et al.Pageof 15