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SLAS Discovery : Advancing Life Sciences R & D
|
August 16, 2024
Development of a sensitive high-throughput enzymatic assay capable of measuring sub-nanomolar inhibitors of SARS-CoV2 Mpro
Peter Kovar, Paul L Richardson, Alla Korepanova, et al.
Journal of Medicinal Chemistry
|
April 29, 2005
1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyanopyrazin-2-yl)ureas [correction of cyanopyrazi] as potent and selective inhibitors of Chk1 kinase: synthesis, preliminary SAR, and biological activities
Gary T Wang, Gaoquan Li, Robert A Mantei, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 25, 2008
Investigation of novel 7,8-disubstituted-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-ones as potent Chk1 inhibitors
Lisa A Hasvold, Le Wang, Magdalena Przytulinska, et al.
Journal of Medicinal Chemistry
|
March 14, 2007
Structure-based design, synthesis, and biological evaluation of potent and selective macrocyclic checkpoint kinase 1 inhibitors
Zhi-Fu Tao, Le Wang, Kent D Stewart, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2007
Discovery of 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2'-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors
Zhi-Fu Tao, Gaoquan Li, Yunsong Tong, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 11, 2007
Pyrazolo[3,4-d]pyrimidines as potent inhibitors of the insulin-like growth factor receptor (IGF-IR)
Robert D Hubbard, Nwe Y Bamaung, Fabio Palazzo, et al.
Journal of Biomolecular Screening
|
September 8, 2006
Kinase drug discovery by affinity selection/mass spectrometry (ASMS): application to DNA damage checkpoint kinase Chk1
Kenneth M Comess, Jonathan D Trumbull, Chang Park, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 1, 2006
Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors
Gaoquan Li, Lisa A Hasvold, Zhi-Fu Tao, et al.
Bioorganic & Medicinal Chemistry
|
February 9, 2007
Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors
Yunsong Tong, Akiyo Claiborne, Kent D Stewart, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 7, 2010
Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases
Gary T Wang, Robert A Mantei, Robert D Hubbard, et al.
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of 4
Search research articles
Search
Showing results (11-20 of 33) with videos related to
Sort By:
Page
of 4
SLAS Discovery : Advancing Life Sciences R & D
|
August 16, 2024
Development of a sensitive high-throughput enzymatic assay capable of measuring sub-nanomolar inhibitors of SARS-CoV2 Mpro
Peter Kovar, Paul L Richardson, Alla Korepanova, et al.
Journal of Medicinal Chemistry
|
April 29, 2005
1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyanopyrazin-2-yl)ureas [correction of cyanopyrazi] as potent and selective inhibitors of Chk1 kinase: synthesis, preliminary SAR, and biological activities
Gary T Wang, Gaoquan Li, Robert A Mantei, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 25, 2008
Investigation of novel 7,8-disubstituted-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-ones as potent Chk1 inhibitors
Lisa A Hasvold, Le Wang, Magdalena Przytulinska, et al.
Journal of Medicinal Chemistry
|
March 14, 2007
Structure-based design, synthesis, and biological evaluation of potent and selective macrocyclic checkpoint kinase 1 inhibitors
Zhi-Fu Tao, Le Wang, Kent D Stewart, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2007
Discovery of 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2'-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors
Zhi-Fu Tao, Gaoquan Li, Yunsong Tong, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 11, 2007
Pyrazolo[3,4-d]pyrimidines as potent inhibitors of the insulin-like growth factor receptor (IGF-IR)
Robert D Hubbard, Nwe Y Bamaung, Fabio Palazzo, et al.
Journal of Biomolecular Screening
|
September 8, 2006
Kinase drug discovery by affinity selection/mass spectrometry (ASMS): application to DNA damage checkpoint kinase Chk1
Kenneth M Comess, Jonathan D Trumbull, Chang Park, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 1, 2006
Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors
Gaoquan Li, Lisa A Hasvold, Zhi-Fu Tao, et al.
Bioorganic & Medicinal Chemistry
|
February 9, 2007
Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors
Yunsong Tong, Akiyo Claiborne, Kent D Stewart, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 7, 2010
Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases
Gary T Wang, Robert A Mantei, Robert D Hubbard, et al.
Page
of 4