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Journal of Medicinal Chemistry|June 3, 2014
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding siteGunther Zimmermann, Carsten Schultz-Fademrecht, Philipp Küchler, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|November 4, 2016
Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding SiteSandip Murarka, Pablo Martín-Gago, Carsten Schultz-Fademrecht, et al.
British Journal of Pharmacology|December 17, 2017
Identification of an (-)-englerin A analogue, which antagonizes (-)-englerin A at TRPC1/4/5 channelsHussein N Rubaiy, Tobias Seitz, Sven Hahn, et al.
Biochemical Pharmacology|November 6, 2003
LAV694, a new antiproliferative agent showing improved skin tolerability vs. clinical standards for the treatment of actinic keratosisJesús Medina, Valérie Picarles, Brigitte Greiner, et al.
Science Immunology|August 26, 2018
Gasdermin D plays a vital role in the generation of neutrophil extracellular trapsGabriel Sollberger, Axel Choidas, Garth Lawrence Burn, et al.
Scientific Reports|December 7, 2017
Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cellsKatsuhiko Muraki, Kaori Ohnishi, Akiho Takezawa, et al.
ACS Chemical Biology|April 17, 2018
Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent ProbesJens Bongard, Marian Lorenz, Ingrid R Vetter, et al.
Chemmedchem|April 5, 2019
Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of ActionJens Bongard, Anna Laura Schmitz, Alex Wolf, et al.
Nature Communications|April 21, 2016
Identification of pyrazolopyridazinones as PDEδ inhibitorsBjörn Papke, Sandip Murarka, Holger A Vogel, et al.
Bioorganic & Medicinal Chemistry|January 9, 2014
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agentsRomeo Romagnoli, Pier Giovanni Baraldi, Carlota Lopez-Cara, et al.
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