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Toxicological Sciences : an Official Journal of the Society of Toxicology|June 14, 2011
Aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator expression in human and rat placentas and transcription activity in human trophoblast culturesLucie Stejskalova, Lenka Vecerova, Laura Mesa Peréz, et al.
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association|September 10, 2017
Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulationJan Dusek, Alejandro Carazo, Frantisek Trejtnar, et al.
Biochemical Pharmacology|August 29, 2009
Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 genePetr Pavek, Katerina Pospechova, Lucie Svecova, et al.
EJNMMI Radiopharmacy and Chemistry|April 18, 2024
Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell modelAnna Durinova, Lucie Smutna, Pavel Barta, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 15, 2004
Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and transport of cimetidinePetr Pavek, Gracia Merino, Els Wagenaar, et al.
Toxicology Letters|February 20, 2013
Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174TAlzbeta Kamenickova, Eva Anzenbacherova, Petr Pavek, et al.
British Journal of Pharmacology|February 28, 2016
The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivatorLucie Hyrsova, Tomas Smutny, Alejandro Carazo, et al.
Acta Pharmaceutica Sinica. B|January 31, 2020
The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoidsTomas Smutny, Jan Dusek, Lucie Hyrsova, et al.
Archives of Toxicology|December 24, 2024
The fungicide propiconazole induces hepatic steatosis and activates PXR in a mouse model of diet-induced obesityBrecht Attema, Outi Kummu, Mária Krutáková, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 11, 2003
Examination of the functional activity of P-glycoprotein in the rat placental barrier using rhodamine 123Petr Pavek, Frantisek Staud, Zdenek Fendrich, et al.
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