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Molecular Cell|August 14, 2024
HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stabilityGongshi Bai, Theresa Endres, Ulrike Kühbacher, et al.
Biorxiv : the Preprint Server for Biology|May 25, 2026
H3K27M-driven hypertranscription leads to a new targetable dependency in diffuse midline gliomasSharmistha Pal, Heng Wang, Jacob Geisberg, et al.
Plos Genetics|September 7, 2013
A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndromeBari J Ballew, Vijai Joseph, Saurav De, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 23, 2023
Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical ModelsGonzalo Rodriguez-Berriguete, Marco Ranzani, Remko Prevo, et al.
Frontiers in Immunology|October 10, 2017
Corrigendum: Clinical and Molecular Heterogeneity of RTEL1 DeficiencyCarsten Speckmann, Sushree Sangita Sahoo, Marta Rizzi, et al.
Frontiers in Immunology|May 17, 2017
Clinical and Molecular Heterogeneity of RTEL1 DeficiencyCarsten Speckmann, Sushree Sangita Sahoo, Marta Rizzi, et al.
Nature|March 25, 2015
REV7 counteracts DNA double-strand break resection and affects PARP inhibitionGuotai Xu, J Ross Chapman, Inger Brandsma, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|July 13, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacyHelen M R Robinson, Vera Grinkevich, Jayesh B Majithiya, et al.
American Journal of Human Genetics|December 4, 2018
DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable ImmunodeficiencyClare V Logan, Jennie E Murray, David A Parry, et al.
Cancer Discovery|May 5, 2021
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer EvolutionSubramanian Venkatesan, Mihaela Angelova, Clare Puttick, et al.
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