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Chemical Science|November 23, 2017
Increase of enzyme activity through specific covalent modification with fragmentsJohn F Darby, Masakazu Atobe, James D Firth, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 23, 2025
Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EMZhuowen Li, Nikhil Bharambe, Kashmiri Manishrao Lande, et al.
Elife|June 17, 2021
A signal capture and proofreading mechanism for the KDEL-receptor explains selectivity and dynamic range in ER retrievalAndreas Gerondopoulos, Philipp Bräuer, Tomoaki Sobajima, et al.
Nature Communications|March 28, 2026
Structural basis for pH-responsive amino acid transport via SLC7A4Dimitrios Kolokouris, Anuja Bothra, Takafumi Kato, et al.
ACS Chemical Biology|February 23, 2016
Application of an Integrated GPCR SAR-Modeling Platform To Explain the Activation Selectivity of Human 5-HT2C over 5-HT2BAlexander Heifetz, R Ian Storer, Gordon McMurray, et al.
Structure (London, England : 1993)|April 16, 2024
Molecular basis for pH sensing in the KDEL trafficking receptorZhiyi Wu, Kathryn Smith, Andreas Gerondopoulos, et al.
Molecular Pharmacology|October 5, 2019
Mutational Analysis and Modeling of Negative Allosteric Modulator Binding Sites in AMPA ReceptorsCharlotte Stenum-Berg, Maria Musgaard, Sergei Chavez-Abiega, et al.
Chemical Science|January 15, 2026
Structure-activity relationships can be directly extracted from high-throughput crystallographic evaluation of fragment elaborations in crude reaction mixturesHarold Grosjean, Kate K Fieseler, Rubén Sanchez-Garcia, et al.
Communications Biology|December 12, 2025
Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic aminesEleanor L Mitchell, Emily B Armstrong, Franco Viscarra, et al.
Nature Communications|October 9, 2024
Structural basis for antibiotic transport and inhibition in PepT2Joanne L Parker, Justin C Deme, Simon M Lichtinger, et al.
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