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The Journal of Biological Chemistry
|
December 1, 2020
Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational dynamics to extend antibiotic resistance
Catherine L Tooke, Philip Hinchliffe, Robert A Bonomo, et al.
Organic & Biomolecular Chemistry
|
February 19, 2021
Catalytic mechanism of the colistin resistance protein MCR-1
Reynier Suardíaz, Emily Lythell, Philip Hinchliffe, et al.
RSC Medicinal Chemistry
|
January 22, 2021
Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition
Catherine L Tooke, Philip Hinchliffe, Alen Krajnc, et al.
Antimicrobial Agents and Chemotherapy
|
August 7, 2019
Molecular Basis of Class A β-Lactamase Inhibition by Relebactam
Catherine L Tooke, Philip Hinchliffe, Pauline A Lang, et al.
Journal of Molecular Biology
|
April 9, 2019
β-Lactamases and β-Lactamase Inhibitors in the 21st Century
Catherine L Tooke, Philip Hinchliffe, Eilis C Bragginton, et al.
Journal of the American Chemical Society
|
March 27, 2023
Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase
Catherine L Tooke, Philip Hinchliffe, Michael Beer, et al.
Antimicrobial Agents and Chemotherapy
|
May 4, 2016
Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates
Karina Calvopiña, Klaus-Daniel Umland, Anna M Rydzik, et al.
Antimicrobial Agents and Chemotherapy
|
July 20, 2016
Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-β-Lactamase Identified from a Functional Metagenomic Study
Ramya Salimraj, Lihong Zhang, Philip Hinchliffe, et al.
The Journal of Physical Chemistry. B
|
September 8, 2025
All Roads Lead to Carbinolamine: QM/MM Study of Enzymatic C-N Bond Cleavage in Anaerobic Glycyl Radical Enzyme Choline Trimethylamine-Lyase (CutC)
Marko Hanzevacki, J Jasmin Güven, Philip Hinchliffe, et al.
Scientific Reports
|
September 22, 2019
Mechanistic Insights into β-Lactamase-Catalysed Carbapenem Degradation Through Product Characterisation
Christopher T Lohans, Emily I Freeman, Emma van Groesen, et al.
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Search research articles
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Showing results (11-20 of 51) with videos related to
Sort By:
Page
of 6
The Journal of Biological Chemistry
|
December 1, 2020
Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational dynamics to extend antibiotic resistance
Catherine L Tooke, Philip Hinchliffe, Robert A Bonomo, et al.
Organic & Biomolecular Chemistry
|
February 19, 2021
Catalytic mechanism of the colistin resistance protein MCR-1
Reynier Suardíaz, Emily Lythell, Philip Hinchliffe, et al.
RSC Medicinal Chemistry
|
January 22, 2021
Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition
Catherine L Tooke, Philip Hinchliffe, Alen Krajnc, et al.
Antimicrobial Agents and Chemotherapy
|
August 7, 2019
Molecular Basis of Class A β-Lactamase Inhibition by Relebactam
Catherine L Tooke, Philip Hinchliffe, Pauline A Lang, et al.
Journal of Molecular Biology
|
April 9, 2019
β-Lactamases and β-Lactamase Inhibitors in the 21st Century
Catherine L Tooke, Philip Hinchliffe, Eilis C Bragginton, et al.
Journal of the American Chemical Society
|
March 27, 2023
Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase
Catherine L Tooke, Philip Hinchliffe, Michael Beer, et al.
Antimicrobial Agents and Chemotherapy
|
May 4, 2016
Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates
Karina Calvopiña, Klaus-Daniel Umland, Anna M Rydzik, et al.
Antimicrobial Agents and Chemotherapy
|
July 20, 2016
Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-β-Lactamase Identified from a Functional Metagenomic Study
Ramya Salimraj, Lihong Zhang, Philip Hinchliffe, et al.
The Journal of Physical Chemistry. B
|
September 8, 2025
All Roads Lead to Carbinolamine: QM/MM Study of Enzymatic C-N Bond Cleavage in Anaerobic Glycyl Radical Enzyme Choline Trimethylamine-Lyase (CutC)
Marko Hanzevacki, J Jasmin Güven, Philip Hinchliffe, et al.
Scientific Reports
|
September 22, 2019
Mechanistic Insights into β-Lactamase-Catalysed Carbapenem Degradation Through Product Characterisation
Christopher T Lohans, Emily I Freeman, Emma van Groesen, et al.
Page
of 6