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Clinical Pharmacology and Therapeutics|September 26, 2017
Two Case Studies on How Study Designs Can Be Made More Informative Using Modeling and Simulation ApproachesPhilip J Lowe, Martin Fink, Mark N MiltonJournal of Pharmacokinetics and Pharmacodynamics|January 3, 2021
Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primatesVittal Shivva, Martin Fink, Philip J LoweJournal of Clinical Pharmacology|December 14, 2011
Population pharmacokinetic and pharmacodynamic model-based comparability assessment of a recombinant human Epoetin Alfa and the Biosimilar HX575Xiaoyu Yan, Philip J Lowe, Martin Fink, et al.British Journal of Clinical Pharmacology|March 12, 2011
Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgEPhilip J Lowe, Didier RenardNature Reviews. Drug Discovery|September 1, 2012
The determination and interpretation of the therapeutic index in drug developmentPatrick Y Muller, Mark N MiltonRegulatory Toxicology and Pharmacology : RTP|December 16, 2014
Revision of omalizumab dosing table for dosing every 4 instead of 2 weeks for specific ranges of bodyweight and baseline IgEPhilip J Lowe, Panayiotis Georgiou, Janice CanvinCurrent Drug Metabolism|May 17, 2007
Evaluation of drug-transporter interactions using in vitro and in vivo modelsCindy Q Xia, Mark N Milton, Liang-Shang GanBasic & Clinical Pharmacology & Toxicology|March 1, 2005
On the prediction of the human response: a recycled mechanistic pharmacokinetic/pharmacodynamic approachGuy M L Meno-Tetang, Philip J LoweJournal of Medicinal Chemistry|March 20, 2008
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albuminElisabet Lázaro, Philip J Lowe, Xavier Briand, et al.Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences|May 6, 2009
Markov models for ion channels: versatility versus identifiability and speedMartin Fink, Denis NoblePageof 9