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Molecular Cancer Therapeutics
|
November 18, 2003
Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies
Kyoung Jin P Yoon, Erik J Krull, Christopher L Morton, et al.
Cancer Research
|
October 30, 2003
A prodrug strategy using ONYX-015-based replicating adenoviruses to deliver rabbit carboxylesterase to tumor cells for conversion of CPT-11 to SN-38
Hilde Stubdal, Noah Perin, Marilyn Lemmon, et al.
Biochemical Pharmacology
|
September 14, 2010
Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11
M Jason Hatfield, Lyudmila Tsurkan, Michael Garrett, et al.
Chemico-Biological Interactions
|
February 20, 2016
Carboxylesterases: General detoxifying enzymes
M Jason Hatfield, Robyn A Umans, Janice L Hyatt, et al.
Bioorganic & Medicinal Chemistry
|
July 8, 2011
Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones
Elizabeth I Parkinson, M Jason Hatfield, Lyudmila Tsurkan, et al.
Molecular Cancer Therapeutics
|
July 5, 2006
Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy
K Jin Yoon, Jianjun Qi, Joanna S Remack, et al.
Cancer Research
|
August 3, 2005
Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan
Edyta Tyminski, Stanley Leroy, Kinya Terada, et al.
Bioorganic & Medicinal Chemistry
|
April 3, 2007
Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils
Latorya D Hicks, Janice L Hyatt, Teri Moak, et al.
Molecular Therapy. Nucleic Acids
|
August 8, 2013
Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs
Kazue Kasai, Hiroshi Nakashima, Fang Liu, et al.
Journal of Medicinal Chemistry
|
November 26, 2010
Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2-ethanediones: potent, selective carboxylesterase inhibitors
Brandon M Young, Janice L Hyatt, David C Bouck, et al.
Page
of 9
Search research articles
Search
Showing results (51-60 of 87) with videos related to
Sort By:
Page
of 9
Molecular Cancer Therapeutics
|
November 18, 2003
Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies
Kyoung Jin P Yoon, Erik J Krull, Christopher L Morton, et al.
Cancer Research
|
October 30, 2003
A prodrug strategy using ONYX-015-based replicating adenoviruses to deliver rabbit carboxylesterase to tumor cells for conversion of CPT-11 to SN-38
Hilde Stubdal, Noah Perin, Marilyn Lemmon, et al.
Biochemical Pharmacology
|
September 14, 2010
Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11
M Jason Hatfield, Lyudmila Tsurkan, Michael Garrett, et al.
Chemico-Biological Interactions
|
February 20, 2016
Carboxylesterases: General detoxifying enzymes
M Jason Hatfield, Robyn A Umans, Janice L Hyatt, et al.
Bioorganic & Medicinal Chemistry
|
July 8, 2011
Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones
Elizabeth I Parkinson, M Jason Hatfield, Lyudmila Tsurkan, et al.
Molecular Cancer Therapeutics
|
July 5, 2006
Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy
K Jin Yoon, Jianjun Qi, Joanna S Remack, et al.
Cancer Research
|
August 3, 2005
Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan
Edyta Tyminski, Stanley Leroy, Kinya Terada, et al.
Bioorganic & Medicinal Chemistry
|
April 3, 2007
Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils
Latorya D Hicks, Janice L Hyatt, Teri Moak, et al.
Molecular Therapy. Nucleic Acids
|
August 8, 2013
Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs
Kazue Kasai, Hiroshi Nakashima, Fang Liu, et al.
Journal of Medicinal Chemistry
|
November 26, 2010
Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2-ethanediones: potent, selective carboxylesterase inhibitors
Brandon M Young, Janice L Hyatt, David C Bouck, et al.
Page
of 9