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Journal of Medicinal Chemistry
|
January 24, 2017
Selective Inhibitors of Human Liver Carboxylesterase Based on a β-Lapachone Scaffold: Novel Reagents for Reaction Profiling
M Jason Hatfield, Jingwen Chen, Ellie M Fratt, et al.
Molecular Pharmacology
|
January 7, 2010
Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin
Andrew C Hemmert, Tamara C Otto, Monika Wierdl, et al.
Journal of Molecular Biology
|
August 6, 2005
Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil
Christopher D Fleming, Sompop Bencharit, Carol C Edwards, et al.
Journal of Medicinal Chemistry
|
August 19, 2005
Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety
Janice L Hyatt, Vanessa Stacy, Randy M Wadkins, et al.
Cancer Research
|
September 5, 2002
Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients
Lars M Wagner, Sylvie M Guichard, Rebecca A Burger, et al.
Cancer Research
|
January 11, 2007
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma
Mary K Danks, K Jin Yoon, Rebecca A Bush, et al.
Journal of Medicinal Chemistry
|
April 15, 2005
Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases
Randy M Wadkins, Janice L Hyatt, Xin Wei, et al.
Journal of Medicinal Chemistry
|
October 19, 2007
Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1
Janice L Hyatt, Randy M Wadkins, Lyudmila Tsurkan, et al.
Molecular Therapy Oncolytics
|
March 28, 2017
Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma
Margarita Gutova, Leanne Goldstein, Marianne Metz, et al.
Stem Cells Translational Medicine
|
October 30, 2013
Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use
Marianne Z Metz, Margarita Gutova, Simon F Lacey, et al.
Page
of 9
Search research articles
Search
Showing results (71-80 of 87) with videos related to
Sort By:
Page
of 9
Journal of Medicinal Chemistry
|
January 24, 2017
Selective Inhibitors of Human Liver Carboxylesterase Based on a β-Lapachone Scaffold: Novel Reagents for Reaction Profiling
M Jason Hatfield, Jingwen Chen, Ellie M Fratt, et al.
Molecular Pharmacology
|
January 7, 2010
Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin
Andrew C Hemmert, Tamara C Otto, Monika Wierdl, et al.
Journal of Molecular Biology
|
August 6, 2005
Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil
Christopher D Fleming, Sompop Bencharit, Carol C Edwards, et al.
Journal of Medicinal Chemistry
|
August 19, 2005
Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety
Janice L Hyatt, Vanessa Stacy, Randy M Wadkins, et al.
Cancer Research
|
September 5, 2002
Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients
Lars M Wagner, Sylvie M Guichard, Rebecca A Burger, et al.
Cancer Research
|
January 11, 2007
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma
Mary K Danks, K Jin Yoon, Rebecca A Bush, et al.
Journal of Medicinal Chemistry
|
April 15, 2005
Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases
Randy M Wadkins, Janice L Hyatt, Xin Wei, et al.
Journal of Medicinal Chemistry
|
October 19, 2007
Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1
Janice L Hyatt, Randy M Wadkins, Lyudmila Tsurkan, et al.
Molecular Therapy Oncolytics
|
March 28, 2017
Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma
Margarita Gutova, Leanne Goldstein, Marianne Metz, et al.
Stem Cells Translational Medicine
|
October 30, 2013
Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use
Marianne Z Metz, Margarita Gutova, Simon F Lacey, et al.
Page
of 9