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Oncotarget|October 30, 2016
Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitorsSteffanie L Furtek, Christopher J Matheson, Donald S Backos, et al.
Trends in Cancer|July 19, 2017
Selective Targeting of RSK Isoforms in CancerKimberly A Casalvieri, Christopher J Matheson, Donald S Backos, et al.
Data in Brief|March 27, 2020
Molecular docking of substituted pteridinones and pyrimidines to the ATP-binding site of the N-terminal domain of RSK2 and associated MM/GBSA and molecular field datasetsKimberly A Casalvieri, Christopher J Matheson, Donald S Backos, et al.
Bioorganic & Medicinal Chemistry|January 27, 2020
Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity studyKimberly A Casalvieri, Christopher J Matheson, Donald S Backos, et al.
Chemmedchem|June 9, 2018
Development of Potent Pyrazolopyrimidinone-Based WEE1 Inhibitors with Limited Single-Agent Cytotoxicity for Cancer TherapyChristopher J Matheson, Kimberly A Casalvieri, Donald S Backos, et al.
Journal of Medicinal Chemistry|January 29, 2025
Small Molecule Modulators of AMP-Activated Protein Kinase (AMPK) Activity and Their Potential in Cancer TherapyJuliet E Strang, Daniel D Astridge, Vu T Nguyen, et al.
ACS Chemical Biology|January 6, 2016
Strategies and Approaches of Targeting STAT3 for Cancer TreatmentSteffanie L Furtek, Donald S Backos, Christopher J Matheson, et al.
Molecules (Basel, Switzerland)|October 14, 2023
The Lateral Metalation of Isoxazolo[3,4-d]pyridazinones towards Hit-to-Lead Development of Selective Positive Modulators of Metabotropic Glutamate ReceptorsChristina A Gates, Donald S Backos, Philip Reigan, et al.
Molecular Pharmacology|July 11, 2006
The bioreduction of a series of benzoquinone ansamycins by NAD(P)H:quinone oxidoreductase 1 to more potent heat shock protein 90 inhibitors, the hydroquinone ansamycinsWenchang Guo, Philip Reigan, David Siegel, et al.
Cancer Research|November 4, 2005
Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibitionWenchang Guo, Philip Reigan, David Siegel, et al.
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