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Molecular Cancer Therapeutics|October 15, 2013
Inhibition of Wee1 sensitizes cancer cells to antimetabolite chemotherapeutics in vitro and in vivo, independent of p53 functionalityAnnemie A Van Linden, Dmitry Baturin, James B Ford, et al.
Biorxiv : the Preprint Server for Biology|January 7, 2025
BRAFV600 and ErbB inhibitors directly activate GCN2 in an off-target manner to limit cancer cell proliferationC Ryland Ill, Nasreen C Marikar, Vu Nguyen, et al.
Cancer Research|June 20, 2012
Manganese superoxide dismutase regulates a metabolic switch during the mammalian cell cycleEhab H Sarsour, Amanda L Kalen, Zhen Xiao, et al.
Bioorganic & Medicinal Chemistry|October 10, 2020
10-N-heterocylic aryl-isoxazole-amides (AIMs) have robust anti-tumor activity against breast and brain cancer cell lines and useful fluorescence propertiesMatthew J Weaver, Sascha Stump, Michael J Campbell, et al.
Molecular Cancer Therapeutics|January 2, 2016
Structure-Based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary TumorsWeipeng Xiong, Christopher J Matheson, Mei Xu, et al.
Chemico-Biological Interactions|January 26, 2013
ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein-protein interactions with HPRT1Vasilis Vasiliou, Monica Sandoval, Donald S Backos, et al.
Molecular Cancer Therapeutics|January 24, 2026
Chromobox2 inhibition: a novel activity of alisertib, an aurora A kinase inhibitorTomomi M Yamamoto, Ritsuko Iwanaga, Elizabeth R Woodruff, et al.
Journal of Medicinal Chemistry|October 13, 2006
Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugatesLanyan Fang, Robert F Battisti, Hao Cheng, et al.
Neurochemical Research|June 8, 2013
Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastomaDonald S Backos, Kristofer S Fritz, Debbie G McArthur, et al.
ACS Chemical Biology|January 9, 2016
A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma CellsChristopher J Matheson, Sujatha Venkataraman, Vladimir Amani, et al.
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