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International Journal of Molecular Sciences|November 11, 2022
Review of the Existing Translational Pharmacokinetics Modeling Approaches Specific to Monoclonal Antibodies (mAbs) to Support the First-In-Human (FIH) Dose SelectionBlaise Pasquiers, Salih Benamara, Mathieu Felices, et al.Pituitary|February 21, 2014
Central hypothyroidism in adults: better understanding for better careSolange Grunenwald, Philippe CaronBiopharmaceutics & Drug Disposition|July 22, 2014
Comparing translational population-PBPK modelling of brain microdialysis with bottom-up prediction of brain-to-plasma distribution in rat and humanKathryn Ball, François Bouzom, Jean-Michel Scherrmann, et al.Drug and Alcohol Dependence|January 22, 2013
Respiratory effects of diazepam/methadone combination in rats: a study based on concentration/effect relationshipsLucie Chevillard, Xavier Declèves, Frédéric J Baud, et al.Journal of Pharmaceutical Sciences|August 7, 2012
Development of a physiologically based pharmacokinetic model for the rat central nervous system and determination of an in vitro-in vivo scaling methodology for the blood-brain barrier permeability of two transporter substrates, morphine and oxycodoneKathryn Ball, François Bouzom, Jean-Michel Scherrmann, et al.Computational and Structural Biotechnology Journal|July 11, 2024
Mechanistic insights into P-glycoprotein ligand transport and inhibition revealed by enhanced molecular dynamics simulationsAhmad Elbahnsi, Balint Dudas, Salvatore Cisternino, et al.British Journal of Pharmacology|July 17, 2015
A polyspecific drug/proton antiporter mediates diphenhydramine and clonidine transport at the mouse blood-retinal barrierHélène Chapy, Pascal André, Xavier Declèves, et al.Current Pharmaceutical Design|June 25, 2013
Human ABC transporters at blood-CNS interfaces as determinants of CNS drug penetrationCatarina Chaves, Ramzi Shawahna, Aude Jacob, et al.The AAPS Journal|June 21, 2013
Physiologically based pharmacokinetic modelling of drug penetration across the blood-brain barrier--towards a mechanistic IVIVE-based approachKathryn Ball, François Bouzom, Jean-Michel Scherrmann, et al.Current Pharmaceutical Design|August 11, 2011
Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: implications for neuropsychopharmacologyNicolas Tournier, Xavier Declèves, Bruno Saubaméa, et al.Pageof 28