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Molecular Metabolism|July 14, 2016
Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine exportPhillip J White, Amanda L Lapworth, Jie An, et al.
JCI Insight|July 7, 2022
Altered branched-chain α-keto acid metabolism is a feature of NAFLD in individuals with severe obesityThomas Grenier-Larouche, Lydia Coulter Kwee, Yann Deleye, et al.
Cell Metabolism|October 14, 2014
Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolismAndrew C Shin, Martin Fasshauer, Nika Filatova, et al.
Cell Metabolism|May 22, 2018
The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate LyasePhillip J White, Robert W McGarrah, Paul A Grimsrud, et al.
Cell|April 23, 2024
BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesisAnthony R P Verkerke, Dandan Wang, Naofumi Yoshida, et al.
Diabetologia|August 10, 2015
Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humansErin L Glynn, Lucy W Piner, Kim M Huffman, et al.
Nature Communications|March 16, 2021
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heartJacquelyn M Walejko, Bridgette A Christopher, Scott B Crown, et al.
American Journal of Preventive Cardiology|May 20, 2024
Lipoprotein subclasses are associated with Hepatic steatosis: insights from the prospective multicenter imaging study for the evaluation of chest pain (PROMISE) clinical trialJulia Karady, Robert W McGarrah, Maggie Nguyen, et al.
Science Translational Medicine|March 23, 2022
Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1bSuraj J Patel, Nan Liu, Sam Piaker, et al.
Cell Reports|November 11, 2020
Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine DepletionPhillip J White, Amanda L Lapworth, Robert W McGarrah, et al.
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