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ACS Pharmacology & Translational Science|February 17, 2023
Signaling Modulation via Minimal C-Terminal Modifications of Apelin-13Léa Théroux, Robin Van Den Hauwe, Kien Trân, et al.Nature Communications|December 12, 2025
Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptorsMarie-Edith Nepveu-Traversy, Malihe Hassanzadeh, Laurent Bruneau-Cossette, et al.Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|October 23, 2025
Structure-activity relationships of contulakin-G: Design, synthesis, and characterization of Thr10 analogs for pain modulationAnnik Lanoie, Sára Ferková, Édouard Caron-Duval, et al.Journal of Medicinal Chemistry|May 27, 2020
Structure-Permeability Relationship of Semipeptidic Macrocycles-Understanding and Optimizing Passive Permeability and Efflux RatioAntoine Le Roux, Émilie Blaise, Pierre-Luc Boudreault, et al.Acta Pharmaceutica Sinica. B|April 27, 2026
A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor functionRebecca L Brouillette, Frédérique Lussier, Émile Breault, et al.Cell Chemical Biology|September 24, 2019
Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human HepatocytesFrançois Béliveau, Aarti Tarkar, Sébastien P Dion, et al.Journal of Medicinal Chemistry|January 4, 2022
Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac EffectsKien Tran, Xavier Sainsily, Jérôme Côté, et al.Journal of Medicinal Chemistry|March 31, 2025
From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 VariantsGabriel Lemieux, Jimena Pérez-Vargas, Antoine Désilets, et al.Nature Communications|May 10, 2025
Structural basis of TMPRSS11D specificity and autocleavage activationBryan J Fraser, Ryan P Wilson, Sára Ferková, et al.Emerging Microbes & Infections|January 30, 2026
TMPRSS2 inhibitors with broad-spectrum efficacy against SARS-CoV-2 (JN.1) and influenza A (H1N1) viruses protect mice from influenza A infectionLianne Presley, Jimena Pérez-Vargas, Anaïs Saintigny, et al.Pageof 7