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CPT: Pharmacometrics & Systems Pharmacology|May 21, 2026
OpenPMX Software for Nonlinear Mixed-Effect Models in Pharmacometrics: Precision Compared With NONMEM First-Order Conditional EstimationDouglas J Eleveld, Jeroen V Koomen, Jasper Stevens, et al.Journal of Clinical Medicine|July 24, 2021
Comment on Morse et al. A Universal Pharmacokinetic Model for Dexmedetomidine in Children and Adults. J. Clin. Med. 2020, 9, 3480Douglas J Eleveld, Pieter J Colin, Laura N Hannivoort, et al.British Journal of Anaesthesia|July 11, 2021
Pharmacokinetic properties of remimazolam in subjects with hepatic or renal impairmentThomas Stöhr, Pieter J Colin, Joachim Ossig, et al.Anesthesiology|October 27, 2023
Target-controlled Infusion of Remimazolam in Healthy Volunteers Shows Some Acute ToleranceRemco Vellinga, Jeroen V Koomen, Douglas J Eleveld, et al.Anesthesiology|March 11, 2025
Influence of Remifentanil on the Pharmacokinetics and Pharmacodynamics of Remimazolam in Healthy VolunteersRemco Vellinga, Jeroen V Koomen, Douglas J Eleveld, et al.British Journal of Anaesthesia|May 1, 2025
Development and analysis of a remimazolam pharmacokinetics and pharmacodynamics model with proposed dosing and concentrations for anaesthesia and sedationDouglas J Eleveld, Pieter J Colin, Johannes P Van den Berg, et al.Anesthesiology|May 12, 2025
Pharmacokinetics and pharmacodynamics of remimazolam for procedural sedation in children and adolescentsPieter J Colin, Lynn H Bichajian, Valentin R Curt, et al.Anesthesiology|December 1, 2021
Dexmedetomidine Clearance Decreases with Increasing Drug Exposure: Implications for Current Dosing Regimens and Target-controlled Infusion Models Assuming Linear PharmacokineticsRicardo Alvarez-Jimenez, Maud A S Weerink, Laura N Hannivoort, et al.Antimicrobial Agents and Chemotherapy|November 6, 2019
Target-Controlled Infusion of Cefepime in Critically Ill PatientsStijn Jonckheere, Nikolaas De Neve, Jan Verbeke, et al.British Journal of Clinical Pharmacology|January 23, 2025
A review on the role of extrapolation as basis for paediatric marketing authorization applications of medicines in the EUCharlotte W M Simons, Loes C H Maton, Maaike van Dartel, et al.Pageof 3