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Journal of Natural Products|May 9, 2025
Discovery of Antibacterial Azaphilone Hybrid Metabolites from Marine-Derived Aspergillus terreus PPS1Yao-Yao Zheng, Xiu Zhang, Ya-Hui Zhang, et al.Bioorganic Chemistry|February 28, 2026
Discovery of 8-sulfonamidoquinolines as anti-proliferative agents against colorectal cancer: design, synthesis, and biological evaluationYanfeng Sun, Yanmei Chen, Zhenhao Wang, et al.Journal of Medicinal Chemistry|November 17, 2020
Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant BehaviorPingyuan Wang, Daniel E Felsing, Haiying Chen, et al.Journal of Virology|September 7, 2018
Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus InfectionEun-Jin Choi, Yuping Ren, Yu Chen, et al.Bioorganic & Medicinal Chemistry Letters|December 28, 2018
Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactionsZhiqing Liu, Paul Wadsworth, Aditya K Singh, et al.Journal of Medicinal Chemistry|September 2, 2025
Discovery of 2-(Pyrazol-4-yl)-quinazolin-4(3H)-one Derivatives as Subnanomolar BRD4 BD2 Inhibitors with High Selectivity via a Bioisosterism ApproachShuxia Chen, Jichen Yang, Qiong Wu, et al.Journal of Medicinal Chemistry|July 1, 2026
Identification of XZ8078 as a Dual-Target Degrader Targeting PARP1 and IKZF3 for Broad Spectrum Anticancer TreatmentXuetao Zhang, Jing He, Yaoyao Li, et al.International Journal of Molecular Sciences|December 24, 2021
Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na+ Channel 1.6 Enables Isoform-Selective ModulationNolan M Dvorak, Cynthia M Tapia, Aditya K Singh, et al.Marine Life Science & Technology|December 1, 2025
MR2938 relieves DSS-induced colitis in mice through inhibiting NF-κB signaling and improving epithelial barrierLing Lv, Mireguli Maimaitiming, Shuli Xia, et al.Journal of Medicinal Chemistry|April 8, 2020
Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological EvaluationZhiqing Liu, Haiying Chen, Pingyuan Wang, et al.Pageof 7