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Journal of Medicinal Chemistry|January 4, 2022
Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding SiteZhiqing Liu, Yi Li, Haiying Chen, et al.
Life (Basel, Switzerland)|September 27, 2025
FGF14 Peptide Derivative Differentially Regulates Nav1.2 and Nav1.6 FunctionParsa Arman, Zahra Haghighijoo, Carmen A Lupascu, et al.
Biorxiv : the Preprint Server for Biology|September 10, 2020
EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K/eNOS-dependent manner during inflammationJie Xiao, Ben Zhang, Zhengchen Su, et al.
Neurobiology of Disease|February 27, 2019
Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetesRyan B Griggs, Diogo F Santos, Don E Laird, et al.
Cell Death and Differentiation|June 19, 2019
SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylationWenyu Zhang, Yanling Feng, Qiqiang Guo, et al.
European Journal of Medicinal Chemistry|August 11, 2023
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activitiesPingyuan Wang, Wen-Ting Zhu, Yajing Wang, et al.
European Journal of Medicinal Chemistry|March 23, 2021
Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitorsPingyuan Wang, Dharini van der Hoeven, Na Ye, et al.
The Journal of Biological Chemistry|October 22, 2021
Intracellular receptor EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K-/eNOS-dependent manner during inflammationJie Xiao, Ben Zhang, Zhengchen Su, et al.
Communications Biology|January 3, 2026
The p53 R181C mutation accumulates through impaired deacetylation by Sirt1 and facilitates tumor developmentErli Wang, Liangzi Cao, Wendong Guo, et al.
EMBO Molecular Medicine|January 18, 2023
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistanceLi-Min Wang, Pingyuan Wang, Xiao-Min Chen, et al.
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