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Cells|April 30, 2021
Rho Family GTPases and Rho GEFs in Glucose HomeostasisPolly A Machin, Elpida Tsonou, David C Hornigold, et al.Scientific Reports|August 5, 2025
P-Rex2 suppresses glucose uptake into liver and skeletal muscle through different adaptor functionsElpida Tsonou, Julia Y Chu, Polly A Machin, et al.Frontiers in Immunology|September 12, 2022
Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responsesKirsti Hornigold, Julia Y Chu, Stephen A Chetwynd, et al.Frontiers in Immunology|June 29, 2023
Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosisPolly A Machin, Anna-Karin E Johnsson, Ellie J Massey, et al.Cell Reports|October 5, 2025
P-Rex1 limits glucose clearance and suppresses hepatocyte glucose uptake and mitochondrial metabolism independently of its Rac-GEF activityJulia Y Chu, Elpida Tsonou, Polly A Machin, et al.Frontiers in Immunology|December 11, 2023
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responsesKirsti Hornigold, Martin J Baker, Polly A Machin, et al.Pageof 1