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Journal of Chemical Information and Modeling
|
July 7, 2022
Prediction Accuracy of Production ADMET Models as a Function of Version: Activity Cliffs Rule
Robert P Sheridan, J Chris Culberson, Elizabeth Joshi, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 25, 2006
Synthesis and SAR of alpha-sulfonylcarboxylic acids as potent matrix metalloproteinase inhibitors
Yue-Mei Zhang, Xiaodong Fan, Bangping Xiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2011
Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategy
Lawrence J Wilson, Bingbing Wang, Shyh-Ming Yang, et al.
Journal of Chemical Information and Modeling
|
March 25, 2020
Experimental Error, Kurtosis, Activity Cliffs, and Methodology: What Limits the Predictivity of Quantitative Structure-Activity Relationship Models?
Robert P Sheridan, Prabha Karnachi, Matthew Tudor, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 19, 2007
beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification
Shyh-Ming Yang, Robert H Scannevin, Bingbing Wang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 23, 2008
7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: design, synthesis, and biological activity
Terry V Hughes, Stuart L Emanuel, Harold R O'Grady, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 18, 2007
beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 2. Optimization of alpha-amino substituents
Shyh-Ming Yang, Robert H Scannevin, Bingbing Wang, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 6, 2007
1-Hydroxy-2-pyridinone-based MMP inhibitors: synthesis and biological evaluation for the treatment of ischemic stroke
Yue-Mei Zhang, Xiaodong Fan, Devraj Chakaravarty, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 6, 2008
A novel 5-[1,3,4-oxadiazol-2-yl]-N-aryl-4,6-pyrimidine diamine having dual EGFR/HER2 kinase activity: design, synthesis, and biological activity
Terry V Hughes, Guozhang Xu, Steven K Wetter, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development
Zhuming Zhang, Xin-Jie Chu, Jin-Jun Liu, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 12) with videos related to
Sort By:
Page
of 2
Journal of Chemical Information and Modeling
|
July 7, 2022
Prediction Accuracy of Production ADMET Models as a Function of Version: Activity Cliffs Rule
Robert P Sheridan, J Chris Culberson, Elizabeth Joshi, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 25, 2006
Synthesis and SAR of alpha-sulfonylcarboxylic acids as potent matrix metalloproteinase inhibitors
Yue-Mei Zhang, Xiaodong Fan, Bangping Xiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2011
Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategy
Lawrence J Wilson, Bingbing Wang, Shyh-Ming Yang, et al.
Journal of Chemical Information and Modeling
|
March 25, 2020
Experimental Error, Kurtosis, Activity Cliffs, and Methodology: What Limits the Predictivity of Quantitative Structure-Activity Relationship Models?
Robert P Sheridan, Prabha Karnachi, Matthew Tudor, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 19, 2007
beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification
Shyh-Ming Yang, Robert H Scannevin, Bingbing Wang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 23, 2008
7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: design, synthesis, and biological activity
Terry V Hughes, Stuart L Emanuel, Harold R O'Grady, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 18, 2007
beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 2. Optimization of alpha-amino substituents
Shyh-Ming Yang, Robert H Scannevin, Bingbing Wang, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 6, 2007
1-Hydroxy-2-pyridinone-based MMP inhibitors: synthesis and biological evaluation for the treatment of ischemic stroke
Yue-Mei Zhang, Xiaodong Fan, Devraj Chakaravarty, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 6, 2008
A novel 5-[1,3,4-oxadiazol-2-yl]-N-aryl-4,6-pyrimidine diamine having dual EGFR/HER2 kinase activity: design, synthesis, and biological activity
Terry V Hughes, Guozhang Xu, Steven K Wetter, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development
Zhuming Zhang, Xin-Jie Chu, Jin-Jun Liu, et al.
Page
of 2