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Nucleic Acids Research
|
November 11, 2015
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts
Sebastien A Burel, Christopher E Hart, Patrick Cauntay, et al.
Journal of the American Chemical Society
|
February 24, 2021
Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell
Laurent Knerr, Thazha P Prakash, Richard Lee, et al.
Nature Biotechnology
|
August 13, 2021
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS
Tetsuya Nagata, Chrissa A Dwyer, Kie Yoshida-Tanaka, et al.
Science Translational Medicine
|
October 5, 2018
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease
Amber L Southwell, Holly B Kordasiewicz, Douglas Langbehn, et al.
Human Molecular Genetics
|
January 21, 2017
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles
Amber L Southwell, Niels H Skotte, Erika B Villanueva, et al.
Nucleic Acids Research
|
May 12, 2019
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates
Michael E Østergaard, Michaela Jackson, Audrey Low, et al.
Journal of Medicinal Chemistry
|
February 26, 2016
Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes
Thazha P Prakash, Jinghua Yu, Michael T Migawa, et al.
Nucleic Acids Research
|
April 10, 2025
Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles
Michael E Østergaard, Michele Carrer, Brooke A Anderson, et al.
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of 11
Search research articles
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Showing results (101-110 of 108) with videos related to
Sort By:
Page
of 11
You have reached the last page of results.
This site can display upto 108 results.
Nucleic Acids Research
|
November 11, 2015
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts
Sebastien A Burel, Christopher E Hart, Patrick Cauntay, et al.
Journal of the American Chemical Society
|
February 24, 2021
Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell
Laurent Knerr, Thazha P Prakash, Richard Lee, et al.
Nature Biotechnology
|
August 13, 2021
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS
Tetsuya Nagata, Chrissa A Dwyer, Kie Yoshida-Tanaka, et al.
Science Translational Medicine
|
October 5, 2018
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease
Amber L Southwell, Holly B Kordasiewicz, Douglas Langbehn, et al.
Human Molecular Genetics
|
January 21, 2017
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles
Amber L Southwell, Niels H Skotte, Erika B Villanueva, et al.
Nucleic Acids Research
|
May 12, 2019
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates
Michael E Østergaard, Michaela Jackson, Audrey Low, et al.
Journal of Medicinal Chemistry
|
February 26, 2016
Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes
Thazha P Prakash, Jinghua Yu, Michael T Migawa, et al.
Nucleic Acids Research
|
April 10, 2025
Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles
Michael E Østergaard, Michele Carrer, Brooke A Anderson, et al.
Page
of 11