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Journal of Medicinal Chemistry
|
July 18, 2020
Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptides
Mehran Nikan, Michael Tanowitz, Chrissa A Dwyer, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 24, 2004
Biaryl guanidine inhibitors of in vitro HCV-IRES activity
Elizabeth A Jefferson, Punit P Seth, Dale E Robinson, et al.
Nucleic Acids Research
|
March 18, 2020
Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice
Alfred E Chappell, Hans J Gaus, Andres Berdeja, et al.
Nucleic Acid Therapeutics
|
July 21, 2022
The Combination of Mesyl-Phosphoramidate Inter-Nucleotide Linkages and 2'-<i>O</i>-Methyl in Selected Positions in the Antisense Oligonucleotide Enhances the Performance of RNaseH1 Active PS-ASOs
Lingdi Zhang, Xue-Hai Liang, Cheryl Li De Hoyos, et al.
Nucleic Acid Therapeutics
|
April 28, 2017
Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver
Aaron J Donner, Edward V Wancewicz, Heather M Murray, et al.
Nucleic Acids Research
|
April 3, 2012
TricycloDNA-modified oligo-2'-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues--a comparative study of oligonucleotide length, design and chemistry
Sue Murray, Damian Ittig, Erich Koller, et al.
ACS Medicinal Chemistry Letters
|
June 18, 2021
Site-specific Incorporation of 2',5'-Linked Nucleic Acids Enhances Therapeutic Profile of Antisense Oligonucleotides
Thazha P Prakash, Jinghua Yu, Wen Shen, et al.
Nucleic Acids Research
|
February 25, 2016
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
Colton M Miller, Aaron J Donner, Emma E Blank, et al.
Journal of the American Chemical Society
|
March 24, 2020
Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins
Malwina Hyjek-Składanowska, Timothy A Vickers, Agnieszka Napiórkowska, et al.
Journal of Medicinal Chemistry
|
November 10, 2010
Configuration of the 5'-methyl group modulates the biophysical and biological properties of locked nucleic acid (LNA) oligonucleotides
Punit P Seth, Charles R Allerson, Andrew Siwkowski, et al.
Page
of 11
Search research articles
Search
Showing results (51-60 of 108) with videos related to
Sort By:
Page
of 11
Journal of Medicinal Chemistry
|
July 18, 2020
Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptides
Mehran Nikan, Michael Tanowitz, Chrissa A Dwyer, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 24, 2004
Biaryl guanidine inhibitors of in vitro HCV-IRES activity
Elizabeth A Jefferson, Punit P Seth, Dale E Robinson, et al.
Nucleic Acids Research
|
March 18, 2020
Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice
Alfred E Chappell, Hans J Gaus, Andres Berdeja, et al.
Nucleic Acid Therapeutics
|
July 21, 2022
The Combination of Mesyl-Phosphoramidate Inter-Nucleotide Linkages and 2'-<i>O</i>-Methyl in Selected Positions in the Antisense Oligonucleotide Enhances the Performance of RNaseH1 Active PS-ASOs
Lingdi Zhang, Xue-Hai Liang, Cheryl Li De Hoyos, et al.
Nucleic Acid Therapeutics
|
April 28, 2017
Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver
Aaron J Donner, Edward V Wancewicz, Heather M Murray, et al.
Nucleic Acids Research
|
April 3, 2012
TricycloDNA-modified oligo-2'-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues--a comparative study of oligonucleotide length, design and chemistry
Sue Murray, Damian Ittig, Erich Koller, et al.
ACS Medicinal Chemistry Letters
|
June 18, 2021
Site-specific Incorporation of 2',5'-Linked Nucleic Acids Enhances Therapeutic Profile of Antisense Oligonucleotides
Thazha P Prakash, Jinghua Yu, Wen Shen, et al.
Nucleic Acids Research
|
February 25, 2016
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
Colton M Miller, Aaron J Donner, Emma E Blank, et al.
Journal of the American Chemical Society
|
March 24, 2020
Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins
Malwina Hyjek-Składanowska, Timothy A Vickers, Agnieszka Napiórkowska, et al.
Journal of Medicinal Chemistry
|
November 10, 2010
Configuration of the 5'-methyl group modulates the biophysical and biological properties of locked nucleic acid (LNA) oligonucleotides
Punit P Seth, Charles R Allerson, Andrew Siwkowski, et al.
Page
of 11