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Punit P Seth

Showing results (71-80 of 108) with videos related to

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Journal of Medicinal Chemistry|January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal modelsThazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Symposium Series (2004)|September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogsPunit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Research|February 4, 2017
Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptorKarsten Schmidt, Thazha P Prakash, Aaron J Donner, et al.
Bioorganic & Medicinal Chemistry Letters|June 9, 2016
Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytesGarth A Kinberger, Thazha P Prakash, Jinghua Yu, et al.
Journal of the American Chemical Society|September 17, 2011
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotidesMartin Egli, Pradeep S Pallan, Charles R Allerson, et al.
Nucleic Acids Research|March 11, 2015
Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2015
Solid-phase synthesis of 5'-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistryThazha P Prakash, W Brad Wan, Audrey Low, et al.
Molecular Medicine (Cambridge, Mass.)|July 26, 2016
Novel Targeted Therapy for Precursor B Cell Acute Lymphoblastic Leukemia: anti-CD22 Antibody-MXD3 Antisense Oligonucleotide ConjugateNoriko Satake, Connie Duong, Sakiko Yoshida, et al.
Nucleic Acid Therapeutics|November 19, 2021
Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman ImagingPrabuddha Mukherjee, Edita Aksamitiene, Aneesh Alex, et al.
Journal of the American Chemical Society|January 18, 2022
Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Pageof 11

Showing results (71-80 of 108) with videos related to

Sort By:
Pageof 11
Journal of Medicinal Chemistry|January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal modelsThazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Symposium Series (2004)|September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogsPunit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Research|February 4, 2017
Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptorKarsten Schmidt, Thazha P Prakash, Aaron J Donner, et al.
Bioorganic & Medicinal Chemistry Letters|June 9, 2016
Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytesGarth A Kinberger, Thazha P Prakash, Jinghua Yu, et al.
Journal of the American Chemical Society|September 17, 2011
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotidesMartin Egli, Pradeep S Pallan, Charles R Allerson, et al.
Nucleic Acids Research|March 11, 2015
Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2015
Solid-phase synthesis of 5'-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistryThazha P Prakash, W Brad Wan, Audrey Low, et al.
Molecular Medicine (Cambridge, Mass.)|July 26, 2016
Novel Targeted Therapy for Precursor B Cell Acute Lymphoblastic Leukemia: anti-CD22 Antibody-MXD3 Antisense Oligonucleotide ConjugateNoriko Satake, Connie Duong, Sakiko Yoshida, et al.
Nucleic Acid Therapeutics|November 19, 2021
Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman ImagingPrabuddha Mukherjee, Edita Aksamitiene, Aneesh Alex, et al.
Journal of the American Chemical Society|January 18, 2022
Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Pageof 11