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Puranik Purushottamachar

Showing results (1-10 of 34) with videos related to

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Steroids|October 10, 2012
A new simple and high-yield synthesis of 5α-dihydrotestosterone (DHT), a potent androgen receptor agonistPuranik Purushottamachar, Vincent C O Njar
European Journal of Medicinal Chemistry|May 26, 2022
Novel deuterated Mnk1/2 protein degrader VNLG-152R analogs: Synthesis, In vitro Anti-TNBC activities and pharmacokinetics in micePuranik Purushottamachar, Elizabeth Thomas, Retheesh S Thankan, et al.
Cancer Chemotherapy and Pharmacology|May 15, 2012
Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1Abhijit M Godbole, Puranik Purushottamachar, Marlena S Martin, et al.
Bioorganic & Medicinal Chemistry|January 2, 2008
Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenograftsLalji K Gediya, Aashvini Belosay, Aakanksha Khandelwal, et al.
Journal of Medicinal Chemistry|July 22, 2005
A new simple and high-yield synthesis of suberoylanilide hydroxamic acid and its inhibitory effect alone or in combination with retinoids on proliferation of human prostate cancer cellsLalji K Gediya, Pankaj Chopra, Puranik Purushottamachar, et al.
Cancers|February 25, 2023
Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal DegradationElizabeth Thomas, Retheesh S Thankan, Puranik Purushottamachar, et al.
Molecular Cancer Therapeutics|February 16, 2012
Autophagy inhibition synergistically enhances anticancer efficacy of RAMBA, VN/12-1 in SKBR-3 cells, and tumor xenograftsAbhijit M Godbole, Puranik Purushottamachar, Marlena S Martin, et al.
Bioorganic Chemistry|July 1, 2023
Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse ModelRetheesh S Thankan, Elizabeth Thomas, Puranik Purushottamachar, et al.
Oncotarget|July 22, 2015
Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivoAndrew K Kwegyir-Afful, Senthilmurugan Ramalingam, Puranik Purushottamachar, et al.
Steroids|June 11, 2022
Large-scale synthesis of galeterone and lead next generation galeterone analog VNPP433-3βPuranik Purushottamachar, Elizabeth Thomas, Retheesh S Thankan, et al.
Pageof 4

Showing results (1-10 of 34) with videos related to

Sort By:
Pageof 4
Steroids|October 10, 2012
A new simple and high-yield synthesis of 5α-dihydrotestosterone (DHT), a potent androgen receptor agonistPuranik Purushottamachar, Vincent C O Njar
European Journal of Medicinal Chemistry|May 26, 2022
Novel deuterated Mnk1/2 protein degrader VNLG-152R analogs: Synthesis, In vitro Anti-TNBC activities and pharmacokinetics in micePuranik Purushottamachar, Elizabeth Thomas, Retheesh S Thankan, et al.
Cancer Chemotherapy and Pharmacology|May 15, 2012
Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1Abhijit M Godbole, Puranik Purushottamachar, Marlena S Martin, et al.
Bioorganic & Medicinal Chemistry|January 2, 2008
Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenograftsLalji K Gediya, Aashvini Belosay, Aakanksha Khandelwal, et al.
Journal of Medicinal Chemistry|July 22, 2005
A new simple and high-yield synthesis of suberoylanilide hydroxamic acid and its inhibitory effect alone or in combination with retinoids on proliferation of human prostate cancer cellsLalji K Gediya, Pankaj Chopra, Puranik Purushottamachar, et al.
Cancers|February 25, 2023
Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal DegradationElizabeth Thomas, Retheesh S Thankan, Puranik Purushottamachar, et al.
Molecular Cancer Therapeutics|February 16, 2012
Autophagy inhibition synergistically enhances anticancer efficacy of RAMBA, VN/12-1 in SKBR-3 cells, and tumor xenograftsAbhijit M Godbole, Puranik Purushottamachar, Marlena S Martin, et al.
Bioorganic Chemistry|July 1, 2023
Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse ModelRetheesh S Thankan, Elizabeth Thomas, Puranik Purushottamachar, et al.
Oncotarget|July 22, 2015
Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivoAndrew K Kwegyir-Afful, Senthilmurugan Ramalingam, Puranik Purushottamachar, et al.
Steroids|June 11, 2022
Large-scale synthesis of galeterone and lead next generation galeterone analog VNPP433-3βPuranik Purushottamachar, Elizabeth Thomas, Retheesh S Thankan, et al.
Pageof 4