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Cell Reports|August 6, 2023
Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channelsHeng Liu, Maya M Polovitskaya, Linlin Yang, et al.Journal of Medicinal Chemistry|July 25, 2022
General Pharmacological Activation Mechanism of K<sup>+</sup> Channels Bypassing Channel GatesShijie Liu, Peipei Guo, Kun Wang, et al.Cell Reports|June 30, 2026
Structural mechanisms for self-activation of protease-activated receptor 4 by tethered ligandZhikang Xu, Jiacheng He, Zihan Zhou, et al.Proceedings of the National Academy of Sciences of the United States of America|April 6, 2026
Structural insights into measles virus RNA synthesis regulation and pan-paramyxoviral polymerase inhibition by ERDRP-0519Tianjiao Du, Jiening Wang, Chengji Yang, et al.Science China. Life Sciences|February 6, 2024
Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A<sub>2</sub> receptorsYuan Weng, Xinyu Yang, Qiansen Zhang, et al.Journal of Pharmaceutical Analysis|September 8, 2025
GPT2-ICC: A data-driven approach for accurate ion channel identification using pre-trained large language modelsZihan Zhou, Yang Yu, Chengji Yang, et al.Journal of Medicinal Chemistry|January 9, 2019
Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid ChannelHao Chai, Xi Cheng, Bin Zhou, et al.Journal of Medicinal Chemistry|January 3, 2020
Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of <i>N</i>-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor GrowthWeikai Guo, Yajing Xing, Qiansen Zhang, et al.ACS Central Science|April 1, 2024
Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer TreatmentHuang Chen, Aiwu Bian, Wenbo Zhou, et al.International Journal of Biological Macromolecules|March 1, 2025
Rational design strategy for thermostability enhancement of protein-glutaminase and investigation of the underlying mechanismsJiajing Wu, Lina Wang, Yixin Sun, et al.Pageof 5