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Journal of Medicinal Chemistry|May 31, 2022
Scaffold Hopping Strategy to Identify Prostanoid EP4 Receptor Antagonists for Cancer ImmunotherapyWei Wang, Jiacheng He, Junjie Yang, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 14, 2022
Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic CancerHuang Chen, Wenbo Zhou, Aiwu Bian, et al.Journal of Medicinal Chemistry|March 7, 2023
Discovery of 2<i>H</i>-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer ImmunotherapyZhiyuan Cheng, Yijie Wang, Yao Zhang, et al.Proceedings of the National Academy of Sciences of the United States of America|December 15, 2020
Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouseHuiying Li, Qiansen Zhang, Yiran Gu, et al.Nature Chemical Biology|January 3, 2024
A small-molecule activation mechanism that directly opens the KCNQ2 channelShaoying Zhang, Demin Ma, Kun Wang, et al.Journal of Medicinal Chemistry|December 20, 2019
Discovery and Characterization of 1<i>H</i>-1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer ImmunotherapyJun-Jie Yang, Wei-Wei Yu, Long-Long Hu, et al.Nature Chemical Biology|January 15, 2025
Small molecule inhibits KCNQ channels with a non-blocking mechanismJunnan Li, Zhenni Yang, Shaoying Zhang, et al.Journal of Medicinal Chemistry|December 31, 2020
From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic SclerosisBei-Er Jiang, Xingwu Jiang, Qiansen Zhang, et al.Cancer Letters|January 6, 2022
An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivoYajing Xing, Weikai Guo, Min Wu, et al.Journal of Medicinal Chemistry|March 13, 2020
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic InflammationYunguang Qiu, Lu Huang, Jie Fu, et al.Pageof 5