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Science Advances|July 11, 2025
Exogenous activation of the adhesion GPCR ADGRD1/GPR133 protects against bone loss by negatively regulating osteoclastogenesisLiang He, Qiansen Zhang, Yu You, et al.EMBO Molecular Medicine|December 7, 2020
Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancerWeiqiang Lu, Weiwei Yu, Jiacheng He, et al.Cell Research|February 4, 2022
Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effectsQiansen Zhang, Yimin Ren, Yiqing Mo, et al.Nature|October 15, 2025
A conserved H3K14ub-driven H3K9me3 for chromatin compartmentalizationYuanyong Huang, Yimei Sun, Hongyun Qi, et al.The Journal of Clinical Investigation|March 17, 2025
Targeting ubiquitin-independent proteasome with small molecule increases susceptibility in pan-KRAS-mutant cancer modelsShihui Shen, Qiansen Zhang, Yuhan Wang, et al.Science Translational Medicine|November 22, 2019
Selective activation of TWIK-related acid-sensitive K<sup>+</sup> 3 subunit-containing channels is analgesic in rodent modelsPing Liao, Yunguang Qiu, Yiqing Mo, et al.Cell Research|October 1, 2025
Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gatingLing Zhong, Xiaoqing Lin, Xinyu Cheng, et al.Cell Research|April 23, 2022
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumorsXiaomin Wang, Ziqi Chen, Jun Xu, et al.Nature Immunology|February 5, 2025
The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancerJiacheng He, Xiaolei Chai, Qiansen Zhang, et al.Pageof 5