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Biochemical Pharmacology|February 1, 2026
Momordin Ic suppresses breast cancer growth by targeting ACTL8‑dependent glutamine metabolism and PI3K/AKT/mTOR-MYCAo Guo, Bijun Yang, Aolin Xiao Huang, et al.
Biomolecules|June 26, 2025
Brusatol Inhibits Esophageal Squamous Cell Carcinoma Tumorigenesis Through Bad-Mediated Mitochondrial Apoptosis Induction and Anti-Metastasis by Targeting Akt1Yao Ji, Xinxin Zhu, Yi Shi, et al.
Molecular Biomedicine|December 7, 2023
Apolipoprotein E (ApoE) orchestrates adipose tissue inflammation and metabolic disorders through NLRP3 inflammasomeYulin Zhang, Ziwei Cheng, Liyu Hong, et al.
Nature Communications|August 31, 2017
An allosteric ligand-binding site in the extracellular cap of K2P channelsQichao Luo, Liping Chen, Xi Cheng, et al.
European Journal of Medicinal Chemistry|June 23, 2026
A PROTAC-inspired bifunctional small molecule recruits CDK6 to target EYA2 degradation and suppress breast tumor growthYanhui Zhang, Chenchen Kan, Jiaxin Ai, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease|February 5, 2026
Dapagliflozin targets RORγt to improve myocardial ischemia-reperfusion injury-induced heart failure by regulating the CD4+ T cell/Th17 cell axis within cardiac tissueYan Wu, Xuewan Ge, Dongbiao Yu, et al.
Cell Reports|April 18, 2026
NSUN2-mediated GATM m5C methylation regulates creatine metabolism to drive mitochondrial fission and promote renal fibrosisXiaoguo Suo, Mengmeng Zhang, Qi Zhu, et al.
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