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Bioorganic & Medicinal Chemistry Letters|December 14, 2017
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivityHua Gong, David S Weinstein, Zhonghui Lu, et al.ACS Medicinal Chemistry Letters|May 31, 2021
Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and PsoriasisQingjie Liu, Hai-Yun Xiao, Douglas G Batt, et al.Journal of Medicinal Chemistry|October 23, 2019
Rationally Designed, Conformationally Constrained Inverse Agonists of RORγt-Identification of a Potent, Selective Series with Biologic-Like in Vivo EfficacyDavid Marcoux, James J-W Duan, Qing Shi, et al.Breast (Edinburgh, Scotland)|November 12, 2025
Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancerAmandine Billaud, Gisella Figlioli, Clémence Mooser, et al.Pageof 12