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European Journal of Medicinal Chemistry|November 7, 2020
A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentialsQijie Gong, Jiabao Hu, Pengfei Wang, et al.Journal of Medicinal Chemistry|December 28, 2020
Reactive Oxygen Species (ROS)-Responsive Prodrugs, Probes, and Theranostic Prodrugs: Applications in the ROS-Related DiseasesPengfei Wang, Qijie Gong, Jiabao Hu, et al.European Journal of Medicinal Chemistry|July 24, 2021
Rational designed highly sensitive NQO1-activated near-infrared fluorescent probe combined with NQO1 substrates in vivo: An innovative strategy for NQO1-overexpressing cancer theranosticsQijie Gong, Fulai Yang, Jiabao Hu, et al.Angewandte Chemie (International Ed. in English)|August 8, 2022
A Carbon-Carbon Bond Cleavage-Based Prodrug Activation Strategy Applied to β-Lapachone for Cancer-Specific TargetingQijie Gong, Xiang Li, Tian Li, et al.Bioorganic Chemistry|March 23, 2023
Novel NQO1 substrates bearing two nitrogen redox centers: Design, synthesis, molecular dynamics simulations, and antitumor evaluationQijie Gong, Pengfei Wang, Tian Li, et al.European Journal of Medicinal Chemistry|May 13, 2021
Application of cation-π interactions in enzyme-substrate binding: Design, synthesis, biological evaluation, and molecular dynamics insights of novel hydrophilic substrates for NQO1Qijie Gong, Quanwei Yu, Nan Wang, et al.Bioorganic & Medicinal Chemistry|March 21, 2025
Identification of effective anti-osteosarcoma agents via screening of an in-house NQO1-targeted compound libraryXiang Li, Qijie Gong, Jianglin Yu, et al.Journal of Medicinal Chemistry|July 11, 2025
Machine-Learning-Driven Discovery of N-Phenylbenzenesulfonamides as a Novel Chemotype for Lactate Dehydrogenase A Inhibition with Anti-Pancreatic Cancer ActivityQijie Gong, Ying Dong, Jiaqi Liang, et al.Journal of Medicinal Chemistry|August 7, 2024
Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and GoutXinye Yang, Yong Li, Shengqiang Pan, et al.Pageof 1