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Journal of the American Chemical Society|June 30, 2025
Denitrogenative Alkylation of K-Ras(G12D) Inhibits Oncogenic Signaling in Cancer CellsQinheng Zheng, Kevan M Shokat
Organic Letters|March 24, 2017
Aryl Fluorosulfate Trapped Staudinger ReductionGerui Ren, Qinheng Zheng, Hua Wang
The Journal of Organic Chemistry|November 5, 2016
Ethenesulfonyl Fluoride (ESF): An On-Water Procedure for the Kilogram-Scale PreparationQinheng Zheng, Jiajia Dong, K Barry Sharpless
Journal of Medicinal Chemistry|February 15, 2022
Drugging the Next Undruggable KRAS Allele-Gly12AspQinheng Zheng, D Matthew Peacock, Kevan M Shokat
Biorxiv : the Preprint Server for Biology|September 26, 2025
Single-sequence deep learning delivers crystal-quality models of covalent K-Ras G12 hotspot complexesSungwon Jung, Qinheng Zheng, Kevan M Shokat
ACS Chemical Biology|July 9, 2025
Distal Covalent Targeting Suppresses Signaling of Oncogenic K-Ras(G13C) in Cancer CellsQinheng Zheng, Tianfang Shen, Julius Pampel, et al.
Nature Chemical Biology|March 5, 2024
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12DQinheng Zheng, Ziyang Zhang, Keelan Z Guiley, et al.
Angewandte Chemie (International Ed. in English)|October 11, 2016
A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click ChemistryHua-Li Qin, Qinheng Zheng, Grant A L Bare, et al.
Angewandte Chemie (International Ed. in English)|April 4, 2017
Palladium-Catalyzed Fluorosulfonylvinylation of Organic IodidesGao-Feng Zha, Qinheng Zheng, Jing Leng, et al.
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