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Cellular and Molecular Life Sciences : CMLS|March 14, 2023
AAV-Net1 facilitates the trans-differentiation of supporting cells into hair cells in the murine cochleaLiyan Zhang, Yuan Fang, Fangzhi Tan, et al.
Fundamental Research|April 1, 2025
Current AAV-mediated gene therapy in sensorineural hearing lossJieyu Qi, Xiaolong Fu, Liyan Zhang, et al.
Cell Proliferation|March 28, 2023
Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochleaChangling Xu, Jieyu Qi, Xiaojie Hu, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|November 12, 2023
Critical role of TPRN rings in the stereocilia for hearingJieyu Qi, Fangzhi Tan, Liyan Zhang, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|April 4, 2025
AAV-Sparcl1 promotes hair cell regeneration by increasing supporting cell plasticityNianci Li, Fangzhi Tan, Liyan Zhang, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|May 29, 2024
AAV-mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell RegenerationLiyan Zhang, Xin Chen, Xinlin Wang, et al.
Nature Communications|September 18, 2025
Optimized in vivo base editing restores auditory function in a DFNA15 mouse modelMan Wang, Ziyu Zhang, Xiaohan Wang, et al.
Med (New York, N.Y.)|February 28, 2026
Precise and efficient DNA base editing restores normal hearing in adult DFNB9 mouse modelZiyu Zhang, Man Wang, Fangzhi Tan, et al.
ACS Nano|July 15, 2025
Establishment of a Cochlear Organoid Platform for Remodeling the Extracellular MatrixNianci Li, Ziyu Zhang, Liyan Zhang, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|March 23, 2025
Combined AAV-mediated specific Gjb2 expression restores hearing in DFNB1 mouse modelsQiuhan Sun, Fangzhi Tan, Liyan Zhang, et al.
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