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Journal of Medicinal Chemistry
|
May 28, 2004
Integrating fragment assembly and biophysical methods in the chemical advancement of small-molecule antagonists of IL-2: an approach for inhibiting protein-protein interactions
Brian C Raimundo, Johan D Oslob, Andrew C Braisted, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 10, 2008
A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties
Ingrid C Choong, Iana Serafimova, Junfa Fan, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 7, 2015
Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease
R Jeffrey Neitz, Clifford Bryant, Steven Chen, et al.
Journal of Medicinal Chemistry
|
November 25, 2025
Fragment-to-Lead Medicinal Chemistry Publications in 2024: A Tenth Annual Perspective
David G Twigg, Kenta Arai, Michelle R Arkin, et al.
ACS Central Science
|
May 30, 2023
A Systematic Approach to the Discovery of Protein-Protein Interaction Stabilizers
Dyana N Kenanova, Emira J Visser, Johanna M Virta, et al.
Journal of the American Chemical Society
|
September 7, 2023
Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3σ/ERα Protein-Protein Interaction from Nonselective Fragments
Markella Konstantinidou, Emira J Visser, Edmee Vandenboorn, et al.
Journal of Molecular Biology
|
June 1, 2014
Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains
Tsui-Fen Chou, Stacie L Bulfer, Conrad C Weihl, et al.
Nature Communications
|
July 14, 2025
Scaffold-hopping for molecular glues targeting the 14-3-3/ERα complex
Markella Konstantinidou, Marios Zingiridis, Marloes A M Pennings, et al.
ACS Sensors
|
June 8, 2021
Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH
Marcus Y Chin, Anand R Patwardhan, Kean-Hooi Ang, et al.
The Biochemical Journal
|
October 8, 2014
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding
Patrick R Visperas, Jonathan A Winger, Timothy M Horton, et al.
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Search research articles
Search
Showing results (71-80 of 128) with videos related to
Sort By:
Page
of 13
Journal of Medicinal Chemistry
|
May 28, 2004
Integrating fragment assembly and biophysical methods in the chemical advancement of small-molecule antagonists of IL-2: an approach for inhibiting protein-protein interactions
Brian C Raimundo, Johan D Oslob, Andrew C Braisted, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 10, 2008
A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties
Ingrid C Choong, Iana Serafimova, Junfa Fan, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 7, 2015
Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease
R Jeffrey Neitz, Clifford Bryant, Steven Chen, et al.
Journal of Medicinal Chemistry
|
November 25, 2025
Fragment-to-Lead Medicinal Chemistry Publications in 2024: A Tenth Annual Perspective
David G Twigg, Kenta Arai, Michelle R Arkin, et al.
ACS Central Science
|
May 30, 2023
A Systematic Approach to the Discovery of Protein-Protein Interaction Stabilizers
Dyana N Kenanova, Emira J Visser, Johanna M Virta, et al.
Journal of the American Chemical Society
|
September 7, 2023
Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3σ/ERα Protein-Protein Interaction from Nonselective Fragments
Markella Konstantinidou, Emira J Visser, Edmee Vandenboorn, et al.
Journal of Molecular Biology
|
June 1, 2014
Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains
Tsui-Fen Chou, Stacie L Bulfer, Conrad C Weihl, et al.
Nature Communications
|
July 14, 2025
Scaffold-hopping for molecular glues targeting the 14-3-3/ERα complex
Markella Konstantinidou, Marios Zingiridis, Marloes A M Pennings, et al.
ACS Sensors
|
June 8, 2021
Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH
Marcus Y Chin, Anand R Patwardhan, Kean-Hooi Ang, et al.
The Biochemical Journal
|
October 8, 2014
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding
Patrick R Visperas, Jonathan A Winger, Timothy M Horton, et al.
Page
of 13