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Bioorganic & Medicinal Chemistry|August 30, 2008
Tetrahydropyridine-4-carboxamides as novel, potent transient receptor potential vanilloid 1 (TRPV1) antagonistsBrian S Brown, Ryan Keddy, Guo Zhu Zheng, et al.The Journal of Pharmacology and Experimental Therapeutics|July 31, 2007
[3H]A-778317 [1-((R)-5-tert-butyl-indan-1-yl)-3-isoquinolin-5-yl-urea]: a novel, stereoselective, high-affinity antagonist is a useful radioligand for the human transient receptor potential vanilloid-1 (TRPV1) receptorBruce R Bianchi, Rachid El Kouhen, Torben R Neelands, et al.Bioorganic & Medicinal Chemistry Letters|May 12, 2010
Discovery of TRPV1 antagonist ABT-116Brian S Brown, Ryan Keddy, Richard J Perner, et al.The Journal of Pharmacology and Experimental Therapeutics|June 3, 2008
(R)-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) blocks polymodal activation of transient receptor potential vanilloid 1 receptors in vitro and heat-evoked firing of spinal dorsal horn neurons in vivoCarol S Surowy, Torben R Neelands, Bruce R Bianchi, et al.Pain|July 13, 2010
A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain modelPamela S Puttfarcken, Ping Han, Shailen K Joshi, et al.Nature Communications|August 31, 2019
Maximizing binary interactome mapping with a minimal number of assaysSoon Gang Choi, Julien Olivet, Patricia Cassonnet, et al.Annals of Oncology : Official Journal of the European Society for Medical Oncology|January 19, 2018
Activity and safety of afatinib in a window preoperative EORTC study in patients with squamous cell carcinoma of the head and neck (SCCHN)J-P Machiels, P Bossi, J Menis, et al.Pain|March 16, 2011
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulationJun Chen, Shailen K Joshi, Stanley DiDomenico, et al.Journal of Medicinal Chemistry|August 8, 2014
Discovery of (R)-1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): a temperature-neutral transient receptor potential vanilloid-1 (TRPV1) antagonist with analgesic efficacyEric A Voight, Arthur R Gomtsyan, Jerome F Daanen, et al.Pageof 42