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Journal of Virology|January 17, 2020
HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T CellsJérémie Prévost, Cassandra R Edgar, Jonathan Richard, et al.
Acta Neuropathologica|September 12, 2015
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathologyEmma L Clayton, Sarah Mizielinska, James R Edgar, et al.
Nature Communications|May 29, 2023
Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal healthJames L Daly, Chris M Danson, Philip A Lewis, et al.
Biorxiv : the Preprint Server for Biology|September 11, 2023
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung diseaseKyungtae Lim, Eimear N Rutherford, Dawei Sun, et al.
Human Molecular Genetics|June 19, 2015
Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage diseaseJennifer Hirst, James R Edgar, Typhaine Esteves, et al.
Journal of Extracellular Vesicles|February 10, 2024
Bioengineered small extracellular vesicles deliver multiple SARS-CoV-2 antigenic fragments and drive a broad immunological responseHannah K Jackson, Heather M Long, Juan Carlos Yam-Puc, et al.
Biorxiv : the Preprint Server for Biology|January 14, 2021
Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde trafficHazel Stewart, Roberta Palmulli, Kristoffer H Johansen, et al.
EMBO Reports|October 11, 2023
Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus releaseHazel Stewart, Roberta Palmulli, Kristoffer H Johansen, et al.
Neurology. Genetics|September 9, 2016
Complicated spastic paraplegia in patients with AP5Z1 mutations (SPG48)Jennifer Hirst, Marianna Madeo, Katrien Smets, et al.
Brain : a Journal of Neurology|February 27, 2018
Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegiaTimothy Newton, Rachel Allison, James R Edgar, et al.
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