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Journal of Medicinal Chemistry
|
March 19, 2004
Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model
Balu N Balasubramanian, Denis R St Laurent, Mark G Saulnier, et al.
Journal of Medicinal Chemistry
|
April 2, 2005
Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11
Mark G Saulnier, Balu N Balasubramanian, Byron H Long, et al.
Journal of Medicinal Chemistry
|
August 23, 2002
Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities
Kyoung Soon Kim, S David Kimball, Raj N Misra, et al.
Cancer Discovery
|
November 5, 2021
DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition
Elisa Izquierdo, Diana M Carvalho, Alan Mackay, et al.
The Lancet. Child & Adolescent Health
|
December 2, 2019
DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study
Jessica C Pickles, Amy R Fairchild, Thomas J Stone, et al.
Cancer Discovery
|
April 3, 2020
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes
Matthew Clarke, Alan Mackay, Britta Ismer, et al.
Page
of 11
Search research articles
Search
Showing results (101-110 of 106) with videos related to
Sort By:
Page
of 11
You have reached the last page of results.
This site can display upto 106 results.
Journal of Medicinal Chemistry
|
March 19, 2004
Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model
Balu N Balasubramanian, Denis R St Laurent, Mark G Saulnier, et al.
Journal of Medicinal Chemistry
|
April 2, 2005
Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11
Mark G Saulnier, Balu N Balasubramanian, Byron H Long, et al.
Journal of Medicinal Chemistry
|
August 23, 2002
Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities
Kyoung Soon Kim, S David Kimball, Raj N Misra, et al.
Cancer Discovery
|
November 5, 2021
DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition
Elisa Izquierdo, Diana M Carvalho, Alan Mackay, et al.
The Lancet. Child & Adolescent Health
|
December 2, 2019
DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study
Jessica C Pickles, Amy R Fairchild, Thomas J Stone, et al.
Cancer Discovery
|
April 3, 2020
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes
Matthew Clarke, Alan Mackay, Britta Ismer, et al.
Page
of 11