R G Melton - JoVE Visualize

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Journal of Molecular Biology|May 20, 1994

Crystallization and preliminary crystallographic data for an FMN-dependent nitroreductase from Escherichia coli BJ V Skelly, P J Collins, R J Knox, et al.

Expert Opinion on Investigational Drugs|July 5, 2005

Targeting enzymes to cancers--new developmentsK D Bagshawe, P J Burke, R J Knox, et al.

Structure (London, England : 1993)|March 15, 1997

Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapyS Rowsell, R A Pauptit, A D Tucker, et al.

British Journal of Cancer|January 1, 1995

Galactosylated streptavidin for improved clearance of biotinylated intact and F(ab')2 fragments of an anti-tumour antibodyD Marshall, R B Pedley, R G Melton, et al.

British Journal of Cancer|March 1, 1996

Polyethylene glycol modification of a galactosylated streptavidin clearing agent: effects on immunogenicity and clearance of a biotinylated anti-tumour antibodyD Marshall, R B Pedley, J A Boden, et al.

Biochemical Pharmacology|December 15, 1992

The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)--I. Purification and properties of a nitroreductase enzyme from Escherichia coli--a potential enzyme for antibody-directed enzyme prodrug therapy (ADEPT)G M Anlezark, R G Melton, R F Sherwood, et al.

Cancer Research|August 17, 2000

Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapyR J Knox, T C Jenkins, S M Hobbs, et al.

Journal of Immunological Methods|January 14, 1993

Optimisation of small-scale coupling of A5B7 monoclonal antibody to carboxypeptidase G2R G Melton, J M Boyle, G T Rogers, et al.

British Journal of Cancer|January 26, 2005

Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failureS Buchen, D Ngampolo, R G Melton, et al.

Biomedical Peptides, Proteins & Nucleic Acids : Structure, Synthesis & Biological Activity|January 1, 1995

In vitro and in vivo comparison of a randomly coupled antibody fragment-enzyme conjugate with a site-specific conjugateR C Werlen, R E Offord, D C Blakey, et al.

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Showing results (11-20 of 39) with videos related to

Sort By:

Pageof 4

Journal of Molecular Biology|May 20, 1994

Crystallization and preliminary crystallographic data for an FMN-dependent nitroreductase from Escherichia coli BJ V Skelly, P J Collins, R J Knox, et al.

Expert Opinion on Investigational Drugs|July 5, 2005

Targeting enzymes to cancers--new developmentsK D Bagshawe, P J Burke, R J Knox, et al.

Structure (London, England : 1993)|March 15, 1997

Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapyS Rowsell, R A Pauptit, A D Tucker, et al.

British Journal of Cancer|January 1, 1995

Galactosylated streptavidin for improved clearance of biotinylated intact and F(ab')2 fragments of an anti-tumour antibodyD Marshall, R B Pedley, R G Melton, et al.

British Journal of Cancer|March 1, 1996

Polyethylene glycol modification of a galactosylated streptavidin clearing agent: effects on immunogenicity and clearance of a biotinylated anti-tumour antibodyD Marshall, R B Pedley, J A Boden, et al.

Biochemical Pharmacology|December 15, 1992

The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)--I. Purification and properties of a nitroreductase enzyme from Escherichia coli--a potential enzyme for antibody-directed enzyme prodrug therapy (ADEPT)G M Anlezark, R G Melton, R F Sherwood, et al.

Cancer Research|August 17, 2000

Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapyR J Knox, T C Jenkins, S M Hobbs, et al.

Journal of Immunological Methods|January 14, 1993

Optimisation of small-scale coupling of A5B7 monoclonal antibody to carboxypeptidase G2R G Melton, J M Boyle, G T Rogers, et al.

British Journal of Cancer|January 26, 2005

Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failureS Buchen, D Ngampolo, R G Melton, et al.

Biomedical Peptides, Proteins & Nucleic Acids : Structure, Synthesis & Biological Activity|January 1, 1995

In vitro and in vivo comparison of a randomly coupled antibody fragment-enzyme conjugate with a site-specific conjugateR C Werlen, R E Offord, D C Blakey, et al.

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