Showing results (21-30 of 39) with videos related to

Sort By:
Pageof 4
Cancer Research|October 1, 1994
Regression of established breast carcinoma xenografts with antibody-directed enzyme prodrug therapy against c-erbB2 p185S A Eccles, W J Court, G A Box, et al.
Biochemical Pharmacology|June 1, 1990
Carboxypeptidase G2 and trimetrexate cause growth delay of human colonic cancer cells in vitroF Searle, K D Bagshawe, R B Pedley, et al.
British Journal of Cancer|December 1, 1988
A cytotoxic agent can be generated selectively at cancer sitesK D Bagshawe, C J Springer, F Searle, et al.
Biochemical Pharmacology|May 26, 1995
Virtual cofactors for an Escherichia coli nitroreductase enzyme: relevance to reductively activated prodrugs in antibody directed enzyme prodrug therapy (ADEPT)R J Knox, F Friedlos, M Jarman, et al.
Journal of Medicinal Chemistry|December 22, 1995
Optimization of alkylating agent prodrugs derived from phenol and aniline mustards: a new clinical candidate prodrug (ZD2767) for antibody-directed enzyme prodrug therapy (ADEPT)C J Springer, R Dowell, P J Burke, et al.
British Journal of Cancer|December 1, 1990
Disposition of the prodrug 4-(bis (2-chloroethyl) amino) benzoyl-L-glutamic acid and its active parent drug in miceP Antoniw, C J Springer, K D Bagshawe, et al.
Cancer|February 1, 1994
Galactosylated antibodies and antibody-enzyme conjugates in antibody-directed enzyme prodrug therapyS K Sharma, K D Bagshawe, P J Burke, et al.
British Journal of Cancer|March 1, 1986
The potential of carboxypeptidase G2-antibody conjugates as anti-tumour agents. I. Preparation of antihuman chorionic gonadotrophin-carboxypeptidase G2 and cytotoxicity of the conjugate against JAR choriocarcinoma cells in vitroF Searle, C Bier, R G Buckley, et al.
Biochemical Pharmacology|August 25, 1995
Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductaseG M Anlezark, R G Melton, R F Sherwood, et al.
Disease Markers|May 1, 1991
Antibody directed enzyme prodrug therapy (ADEPT): clinical reportK D Bagshawe, S K Sharma, C J Springer, et al.
Pageof 4