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R G Moran

Showing results (51-60 of 75) with videos related to

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The Journal of Biological Chemistry|January 5, 1989
A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesisG P Beardsley, B A Moroson, E C Taylor, et al.
Somatic Cell and Molecular Genetics|November 1, 1986
Assignment of genes encoding dihydrofolate reductase and hexosaminidase B to Mus musculus chromosome 13A M Killary, R J Leach, R G Moran, et al.
Biochemical Pharmacology|January 1, 1984
Methotrexate analogues--XVII. Antitumor activity of 4-amino-4-deoxy-N10-methylpteroyl-D,L-homocysteic acid and its dual inhibition of dihydrofolate reductase and folyl polyglutamate synthetaseA Rosowsky, R G Moran, R Forsch, et al.
Journal of Medicinal Chemistry|May 1, 1984
Methotrexate analogues. 19. Replacement of the glutamate side chain in classical antifolates by L-homocysteic acid and L-cysteic acid: effect on enzyme inhibition and antitumor activityA Rosowsky, R A Forsch, J H Freisheim, et al.
Journal of Medicinal Chemistry|April 1, 1988
Methotrexate analogues. 31. Meta and ortho isomers of aminopterin, compounds with a double bond in the side chain, and a novel analogue modified at the alpha-carbon: chemical and in vitro biological studiesA Rosowsky, H Bader, R A Forsch, et al.
Journal of Medicinal Chemistry|July 1, 1988
Methotrexate analogues. 32. Chain extension, alpha-carboxyl deletion, and gamma-carboxyl replacement by sulfonate and phosphonate: effect on enzyme binding and cell-growth inhibitionA Rosowsky, R A Forsch, R G Moran, et al.
Cancer Research|February 1, 1982
In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomasC P Spears, A H Shahinian, R G Moran, et al.
Molecular Pharmacology|January 1, 1985
Structural features of 4-amino antifolates required for substrate activity with mammalian folylpolyglutamate synthetaseR G Moran, P D Colman, A Rosowsky, et al.
Journal of Medicinal Chemistry|May 1, 1992
Side chain modified 5-deazafolate and 5-deazatetrahydrofolate analogues as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: synthesis and in vitro biological evaluationA Rosowsky, R A Forsch, V E Reich, et al.
Journal of Medicinal Chemistry|July 1, 1988
Methotrexate analogues. 33. N delta-acyl-N alpha-(4-amino-4-deoxypteroyl)-L-ornithine derivatives: synthesis and in vitro antitumor activityA Rosowsky, H Bader, C A Cucchi, et al.
Pageof 8

Showing results (51-60 of 75) with videos related to

Sort By:
Pageof 8
The Journal of Biological Chemistry|January 5, 1989
A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesisG P Beardsley, B A Moroson, E C Taylor, et al.
Somatic Cell and Molecular Genetics|November 1, 1986
Assignment of genes encoding dihydrofolate reductase and hexosaminidase B to Mus musculus chromosome 13A M Killary, R J Leach, R G Moran, et al.
Biochemical Pharmacology|January 1, 1984
Methotrexate analogues--XVII. Antitumor activity of 4-amino-4-deoxy-N10-methylpteroyl-D,L-homocysteic acid and its dual inhibition of dihydrofolate reductase and folyl polyglutamate synthetaseA Rosowsky, R G Moran, R Forsch, et al.
Journal of Medicinal Chemistry|May 1, 1984
Methotrexate analogues. 19. Replacement of the glutamate side chain in classical antifolates by L-homocysteic acid and L-cysteic acid: effect on enzyme inhibition and antitumor activityA Rosowsky, R A Forsch, J H Freisheim, et al.
Journal of Medicinal Chemistry|April 1, 1988
Methotrexate analogues. 31. Meta and ortho isomers of aminopterin, compounds with a double bond in the side chain, and a novel analogue modified at the alpha-carbon: chemical and in vitro biological studiesA Rosowsky, H Bader, R A Forsch, et al.
Journal of Medicinal Chemistry|July 1, 1988
Methotrexate analogues. 32. Chain extension, alpha-carboxyl deletion, and gamma-carboxyl replacement by sulfonate and phosphonate: effect on enzyme binding and cell-growth inhibitionA Rosowsky, R A Forsch, R G Moran, et al.
Cancer Research|February 1, 1982
In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomasC P Spears, A H Shahinian, R G Moran, et al.
Molecular Pharmacology|January 1, 1985
Structural features of 4-amino antifolates required for substrate activity with mammalian folylpolyglutamate synthetaseR G Moran, P D Colman, A Rosowsky, et al.
Journal of Medicinal Chemistry|May 1, 1992
Side chain modified 5-deazafolate and 5-deazatetrahydrofolate analogues as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: synthesis and in vitro biological evaluationA Rosowsky, R A Forsch, V E Reich, et al.
Journal of Medicinal Chemistry|July 1, 1988
Methotrexate analogues. 33. N delta-acyl-N alpha-(4-amino-4-deoxypteroyl)-L-ornithine derivatives: synthesis and in vitro antitumor activityA Rosowsky, H Bader, C A Cucchi, et al.
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